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PubMed code 28929751

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249988
PNG
(CHEMBL4061005)
Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1
Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3
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n/an/an/a 2n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249990
PNG
(CHEMBL4090022)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C33H30F2N4O2/c34-26-16-6-2-12-22(26)30-36-28-18-8-4-14-24(28)32(40)38(30)20-10-1-11-21-39-31(23-13-3-7-17-27(23)35)37-29-19-9-5-15-25(29)33(39)41/h2-9,12-19,30-31,36-37H,1,10-11,20-21H2
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n/an/an/a 8n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249980
PNG
(CHEMBL4091313)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C35H34F2N4O2/c36-28-18-8-4-14-24(28)32-38-30-20-10-6-16-26(30)34(42)40(32)22-12-2-1-3-13-23-41-33(25-15-5-9-19-29(25)37)39-31-21-11-7-17-27(31)35(41)43/h4-11,14-21,32-33,38-39H,1-3,12-13,22-23H2
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n/an/an/a 9n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249984
PNG
(CHEMBL4098417)
Show SMILES Fc1ccccc1[C@H]1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1[C@H](Nc2ccccc2C1=O)c1ccccc1F |r|
Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2/t32-,33-/m0/s1
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n/an/an/a 1.12E+3n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249992
PNG
(CHEMBL4090695)
Show SMILES Fc1ccccc1[C@@H]1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1[C@@H](Nc2ccccc2C1=O)c1ccccc1F |r|
Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2/t32-,33-/m1/s1
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n/an/an/a 2.30n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249988
PNG
(CHEMBL4061005)
Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1
Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3
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n/an/an/a 0.600n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249979
PNG
(CHEMBL4061982)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C34H32F2N4O2/c35-27-17-7-3-13-23(27)31-37-29-19-9-5-15-25(29)33(41)39(31)21-11-1-2-12-22-40-32(24-14-4-8-18-28(24)36)38-30-20-10-6-16-26(30)34(40)42/h3-10,13-20,31-32,37-38H,1-2,11-12,21-22H2
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n/an/an/a 4n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249989
PNG
(CHEMBL1387422)
Show SMILES CC(CNC(=O)CCCn1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1)c1ccccc1
Show InChI InChI=1S/C27H31N5O2/c1-18-12-14-23(15-13-18)32-21(4)25-20(3)29-31(27(34)26(25)30-32)16-8-11-24(33)28-17-19(2)22-9-6-5-7-10-22/h5-7,9-10,12-15,19H,8,11,16-17H2,1-4H3,(H,28,33)
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n/an/an/a 2.20n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249991
PNG
(CHEMBL4069561)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CC1CCC(CN2C(Nc3ccccc3C2=O)c2ccccc2F)CC1 |(30.58,-33,;31.92,-32.24,;33.26,-33.01,;34.59,-32.25,;34.59,-30.7,;33.26,-29.93,;31.94,-30.7,;30.61,-29.92,;29.26,-30.69,;27.92,-29.91,;26.59,-30.69,;25.26,-29.91,;25.26,-28.37,;26.59,-27.6,;27.92,-28.36,;29.26,-27.58,;29.26,-26.04,;30.61,-28.36,;31.94,-27.6,;31.95,-26.06,;33.29,-25.3,;33.3,-23.76,;31.97,-22.99,;31.98,-21.45,;33.32,-20.68,;33.32,-19.15,;34.67,-18.4,;36,-19.17,;37.33,-18.43,;38.64,-19.2,;38.62,-20.74,;37.29,-21.49,;35.98,-20.71,;34.64,-21.47,;34.63,-23.01,;31.99,-18.38,;30.66,-19.14,;29.33,-18.37,;29.33,-16.82,;30.67,-16.06,;32,-16.84,;33.34,-16.07,;30.63,-23.75,;30.62,-25.29,)|
Show InChI InChI=1S/C36H34F2N4O2/c37-29-13-5-1-9-25(29)33-39-31-15-7-3-11-27(31)35(43)41(33)21-23-17-19-24(20-18-23)22-42-34(26-10-2-6-14-30(26)38)40-32-16-8-4-12-28(32)36(42)44/h1-16,23-24,33-34,39-40H,17-22H2
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n/an/an/a 15n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249993
PNG
(CHEMBL4083592)
Show SMILES O=C1N(c2cccc3cccc1c23)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H15NO/c25-23-20-10-4-8-18-9-5-11-21(22(18)20)24(23)19-14-12-17(13-15-19)16-6-2-1-3-7-16/h1-15H
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n/an/an/a 227n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249978
PNG
(CHEMBL4084687)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCN1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C32H28F2N4O2/c33-25-15-5-1-11-21(25)29-35-27-17-7-3-13-23(27)31(39)37(29)19-9-10-20-38-30(22-12-2-6-16-26(22)34)36-28-18-8-4-14-24(28)32(38)40/h1-8,11-18,29-30,35-36H,9-10,19-20H2
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n/an/an/a 76n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249987
PNG
(CHEMBL4082888)
Show SMILES Cc1n(nc2c1c(C)nn(CCCN1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1
Show InChI InChI=1S/C36H38FN7O2/c1-23-13-15-27(16-14-23)44-25(3)32-24(2)39-42(36(46)33(32)40-44)20-8-19-41-21-17-26(18-22-41)43-34(28-9-4-6-11-30(28)37)38-31-12-7-5-10-29(31)35(43)45/h4-7,9-16,26,34,38H,8,17-22H2,1-3H3
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n/an/an/a 4n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249985
PNG
(CHEMBL4080394)
Show SMILES Fc1ccccc1[C@H]1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1[C@@H](Nc2ccccc2C1=O)c1ccccc1F |r|
Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2/t32-,33+/m0/s1
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n/an/an/a 33n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249986
PNG
(CHEMBL4073704)
Show SMILES Fc1ccccc1[C@@H]1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1[C@H](Nc2ccccc2C1=O)c1ccccc1F |r|
Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2/t32-,33+/m1/s1
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n/an/an/a 58n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249982
PNG
(CHEMBL4092911)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2
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n/an/an/a 12n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249988
PNG
(CHEMBL4061005)
Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1
Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3
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n/an/an/a 2n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249981
PNG
(CHEMBL4072582)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCOc1ccc(cc1)N1C(Nc2ccccc2C1=O)c1ccccc1F
Show InChI InChI=1S/C36H28F2N4O3/c37-29-13-5-1-9-25(29)33-39-31-15-7-3-11-27(31)35(43)41(33)21-22-45-24-19-17-23(18-20-24)42-34(26-10-2-6-14-30(26)38)40-32-16-8-4-12-28(32)36(42)44/h1-20,33-34,39-40H,21-22H2
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n/an/an/a 16n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50249983
PNG
(CHEMBL4060010)
Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCN1CCC(CN2C(Nc3ccccc3C2=O)c2ccccc2F)CC1
Show InChI InChI=1S/C36H35F2N5O2/c37-29-13-5-1-9-25(29)33-39-31-15-7-3-11-27(31)35(44)42(33)22-21-41-19-17-24(18-20-41)23-43-34(26-10-2-6-14-30(26)38)40-32-16-8-4-12-28(32)36(43)45/h1-16,24,33-34,39-40H,17-23H2
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n/an/an/a 22n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50019865
PNG
(CHEMBL3286929)
Show SMILES C(Oc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1)[C@H](C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1 |r|
Show InChI InChI=1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31-13-5-2-6-14-31/h1-22,30,38,41H,23-28H2/t38-/m1/s1
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n/an/an/a 24n/an/an/an/an/a



School of Pharmacy, Second Military Medical University , Shanghai 200433, China.

Curated by ChEMBL


Assay Description
Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay

J Med Chem 60: 9400-9406 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01243
BindingDB Entry DOI: 10.7270/Q2571FDQ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
* indicates data uncertainty>20%