Affinity Data by PubMed id=2913301

PubMed code 2913301

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020475 (CHEMBL341192 \| [7-Methyl-5-(thiophene-2-carbonyl)-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020464 (CHEMBL135161 \| [5-(2-Methoxycarbonylamino-1H-benzo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020463 (Benzoic acid 5-(2-methoxycarbonylamino-1H-benzoimi...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020478 (CHEMBL133799 \| [5-(4-Cyanomethyl-thiophene-2-carbo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020459 (CHEMBL336862 \| [5-(2-Methoxycarbonylamino-1H-benzo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020480 (CHEMBL422615 \| [5-(2-Methoxycarbonylamino-1H-benzo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM97233 (CHEMBL9514 \| MLS001164242 \| N-[6-(2-thenoyl)-1H-be...) Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cccs1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020479 (CHEMBL133900 \| [5-(2-Methoxycarbonylamino-1H-benzo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020460 (2,2,2-Trifluoro-1-[5-(2-methoxycarbonylamino-1H-be...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020461 (CHEMBL422269 \| [5-(Thiophene-2-carbonyl)-1H-benzoi...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020469 (CHEMBL134616 \| {5-[4-(2,2,2-Trifluoro-acetyl)-thio...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020474 (CHEMBL133155 \| [5-(4-Methyl-thiophene-2-carbonyl)-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020455 (CHEMBL130090 \| [5-(4-Hydroxymethyl-thiophene-2-car...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020454 (CHEMBL133877 \| {5-[4-(tert-Butoxycarbonylamino-met...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020473 (CHEMBL135796 \| [4-Methyl-5-(thiophene-2-carbonyl)-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020472 (CHEMBL336324 \| [5-(4-Aminomethyl-thiophene-2-carbo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50020468 (CHEMBL130169 \| [5-(2-Methoxycarbonylamino-1H-benzo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by ChEMBL					Assay Description Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.				J Med Chem 32: 409-17 (1989) BindingDB Entry DOI: 10.7270/Q2125RN4
Smith Kline & French Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%