Affinity Data by PubMed id=3351853

PubMed code 3351853

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydrofolate reductase (Mus musculus (Mouse))	BDBM50367055 (4-Aminofolic acid \| 4-Aminopteroic acid \| AMINOPTE...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase(DHFR) isolated from L1210 murine leukemia cells				J Med Chem 31: 763-8 (1988) BindingDB Entry DOI: 10.7270/Q24J0FPQ
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mus musculus (Mouse))	BDBM50023405 (3-(Carboxymethyl-{4-[(2,4-diamino-pteridin-6-ylmet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase(DHFR)				J Med Chem 31: 763-8 (1988) BindingDB Entry DOI: 10.7270/Q24J0FPQ
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mus musculus (Mouse))	BDBM50023404 (5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase(DHFR)				J Med Chem 31: 763-8 (1988) BindingDB Entry DOI: 10.7270/Q24J0FPQ
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mus musculus (Mouse))	BDBM50023406 (5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase(DHFR)				J Med Chem 31: 763-8 (1988) BindingDB Entry DOI: 10.7270/Q24J0FPQ
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mus musculus (Mouse))	BDBM50023408 (2-{3-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against dihydrofolate reductase(DHFR) isolated from L1210 murine leukemia cells				J Med Chem 31: 763-8 (1988) BindingDB Entry DOI: 10.7270/Q24J0FPQ
Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%