Found 60 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284642
(CHEMBL283495 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2cccnc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-12-6-5-11-30(31)27-15-13-25(14-16-27)22-43-24-38-33-18-17-29(20-32(33)36(43)46)44(23-26-8-7-19-37-21-26)35(45)28-9-3-2-4-10-28/h2-21,24H,22-23H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284663
(CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...)Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284655
(CHEMBL30015 | N-(4-Hydroxy-benzyl)-N-{3-[2'-(1-met...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccc(O)cc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O3/c1-42-35(39-40-41-42)32-10-6-5-9-31(32)27-15-11-25(12-16-27)22-43-24-38-34-20-17-29(21-33(34)37(43)47)44(23-26-13-18-30(45)19-14-26)36(46)28-7-3-2-4-8-28/h2-21,24,45H,22-23H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284649
(4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284645
(CHEMBL29512 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetra...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O2/c1-42-35(39-40-41-42)32-15-9-8-14-31(32)28-18-16-27(17-19-28)23-43-25-38-34-21-20-30(22-33(34)37(43)46)44(24-26-10-4-2-5-11-26)36(45)29-12-6-3-7-13-29/h2-22,25H,23-24H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284641
(4-[(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES COC(=O)c1ccc(CN(C(=O)c2ccccc2)c2ccc3ncn(Cc4ccc(cc4)-c4ccccc4-c4nnnn4C)c(=O)c3c2)cc1 Show InChI InChI=1S/C39H31N7O4/c1-44-36(41-42-43-44)33-11-7-6-10-32(33)28-16-12-26(13-17-28)23-45-25-40-35-21-20-31(22-34(35)38(45)48)46(37(47)29-8-4-3-5-9-29)24-27-14-18-30(19-15-27)39(49)50-2/h3-22,25H,23-24H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284649
(4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284642
(CHEMBL283495 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2cccnc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-12-6-5-11-30(31)27-15-13-25(14-16-27)22-43-24-38-33-18-17-29(20-32(33)36(43)46)44(23-26-8-7-19-37-21-26)35(45)28-9-3-2-4-10-28/h2-21,24H,22-23H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284674
(2-Methoxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES CCCCCN(C(=O)c1ccccc1OC)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H35N7O3/c1-4-5-10-21-43(36(45)30-13-8-9-14-33(30)46-3)27-19-20-32-31(22-27)35(44)42(24-37-32)23-25-15-17-26(18-16-25)28-11-6-7-12-29(28)34-38-39-40-41(34)2/h6-9,11-20,22,24H,4-5,10,21,23H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284663
(CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...)Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284661
(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284644
(Acetic acid 4-(benzoyl-{3-[2'-(1-methyl-1H-tetrazo...)Show SMILES CC(=O)OCCCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H33N7O4/c1-25(44)47-21-9-8-20-43(35(45)28-10-4-3-5-11-28)29-18-19-33-32(22-29)36(46)42(24-37-33)23-26-14-16-27(17-15-26)30-12-6-7-13-31(30)34-38-39-40-41(34)2/h3-7,10-19,22,24H,8-9,20-21,23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284651
(CHEMBL280908 | N-(2-Ethoxy-ethyl)-N-{3-[2'-(1-meth...)Show SMILES CCOCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-44-20-19-41(33(42)26-9-5-4-6-10-26)27-17-18-31-30(21-27)34(43)40(23-35-31)22-24-13-15-25(16-14-24)28-11-7-8-12-29(28)32-36-37-38-39(32)2/h4-18,21,23H,3,19-20,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284642
(CHEMBL283495 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2cccnc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-12-6-5-11-30(31)27-15-13-25(14-16-27)22-43-24-38-33-18-17-29(20-32(33)36(43)46)44(23-26-8-7-19-37-21-26)35(45)28-9-3-2-4-10-28/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284647
(CHEMBL28917 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES CCCCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O2/c1-3-4-10-21-42(34(43)27-11-6-5-7-12-27)28-19-20-32-31(22-28)35(44)41(24-36-32)23-25-15-17-26(18-16-25)29-13-8-9-14-30(29)33-37-38-39-40(33)2/h5-9,11-20,22,24H,3-4,10,21,23H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284647
(CHEMBL28917 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES CCCCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O2/c1-3-4-10-21-42(34(43)27-11-6-5-7-12-27)28-19-20-32-31(22-28)35(44)41(24-36-32)23-25-15-17-26(18-16-25)29-13-8-9-14-30(29)33-37-38-39-40(33)2/h5-9,11-20,22,24H,3-4,10,21,23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284672
(4-Fluoro-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biph...)Show SMILES CCCCCN(C(=O)c1ccc(F)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H32FN7O2/c1-3-4-7-20-43(34(44)26-14-16-27(36)17-15-26)28-18-19-32-31(21-28)35(45)42(23-37-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-38-39-40-41(33)2/h5-6,8-19,21,23H,3-4,7,20,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284653
(4-Fluoro-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biph...)Show SMILES CCCN(C(=O)c1ccc(F)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C33H28FN7O2/c1-3-18-41(32(42)24-12-14-25(34)15-13-24)26-16-17-30-29(19-26)33(43)40(21-35-30)20-22-8-10-23(11-9-22)27-6-4-5-7-28(27)31-36-37-38-39(31)2/h4-17,19,21H,3,18,20H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284650
(CHEMBL280988 | Furan-2-carboxylic acid {3-[2'-(1-m...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccco2)cc1 Show InChI InChI=1S/C34H26N8O3/c1-40-32(37-38-39-40)28-9-3-2-8-27(28)24-13-11-23(12-14-24)20-41-22-36-30-16-15-26(19-29(30)33(41)43)42(21-25-7-4-5-17-35-25)34(44)31-10-6-18-45-31/h2-19,22H,20-21H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284643
(CHEMBL282777 | N-[2-(2-Methoxy-ethoxy)-ethyl]-N-{3...)Show SMILES COCCOCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O4/c1-40-33(37-38-39-40)30-11-7-6-10-29(30)26-14-12-25(13-15-26)23-41-24-36-32-17-16-28(22-31(32)35(41)44)42(18-19-46-21-20-45-2)34(43)27-8-4-3-5-9-27/h3-17,22,24H,18-21,23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284662
(CHEMBL281890 | DiSodium salt; Phosphoric acid mono...)Show SMILES CCCCN(C(=O)c1ccc(OP([O-])([O-])=O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H32N7O6P/c1-3-4-19-41(33(42)25-13-16-27(17-14-25)47-48(44,45)46)26-15-18-31-30(20-26)34(43)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22H,3-4,19,21H2,1-2H3,(H2,44,45,46)/p-2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284658
(4-(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biph...)Show SMILES CCOC(=O)CCCN(C(=O)c1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H33N7O4/c1-3-47-33(44)14-9-21-43(35(45)27-10-5-4-6-11-27)28-19-20-32-31(22-28)36(46)42(24-37-32)23-25-15-17-26(18-16-25)29-12-7-8-13-30(29)34-38-39-40-41(34)2/h4-8,10-13,15-20,22,24H,3,9,14,21,23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284664
(CHEMBL266480 | N-Butyl-4-fluoro-N-{3-[2'-(1-methyl...)Show SMILES CCCCN(C(=O)c1ccc(F)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H30FN7O2/c1-3-4-19-42(33(43)25-13-15-26(35)16-14-25)27-17-18-31-30(20-27)34(44)41(22-36-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-37-38-39-40(32)2/h5-18,20,22H,3-4,19,21H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284656
(CHEMBL28918 | Pentanoic acid benzyl-{3-[2'-(1-meth...)Show SMILES CCCCC(=O)N(Cc1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O2/c1-3-4-14-33(43)42(23-25-10-6-5-7-11-25)28-19-20-32-31(21-28)35(44)41(24-36-32)22-26-15-17-27(18-16-26)29-12-8-9-13-30(29)34-37-38-39-40(34)2/h5-13,15-21,24H,3-4,14,22-23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284656
(CHEMBL28918 | Pentanoic acid benzyl-{3-[2'-(1-meth...)Show SMILES CCCCC(=O)N(Cc1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O2/c1-3-4-14-33(43)42(23-25-10-6-5-7-11-25)28-19-20-32-31(21-28)35(44)41(24-36-32)22-26-15-17-27(18-16-26)29-12-8-9-13-30(29)34-37-38-39-40(34)2/h5-13,15-21,24H,3-4,14,22-23H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284667
(CHEMBL28816 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C36H27N7O2/c1-41-34(38-39-40-41)31-15-9-8-14-30(31)26-18-16-25(17-19-26)23-42-24-37-33-21-20-29(22-32(33)36(42)45)43(28-12-6-3-7-13-28)35(44)27-10-4-2-5-11-27/h2-22,24H,23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284648
(CHEMBL29722 | N-(4-Hydroxy-butyl)-N-{3-[2'-(1-meth...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(CCCCO)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C34H31N7O3/c1-39-32(36-37-38-39)29-12-6-5-11-28(29)25-15-13-24(14-16-25)22-40-23-35-31-18-17-27(21-30(31)34(40)44)41(19-7-8-20-42)33(43)26-9-3-2-4-10-26/h2-6,9-18,21,23,42H,7-8,19-20,22H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284660
(CHEMBL29654 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES CCCCCN(C(=O)c1ccncc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H32N8O2/c1-3-4-7-20-42(33(43)26-16-18-35-19-17-26)27-14-15-31-30(21-27)34(44)41(23-36-31)22-24-10-12-25(13-11-24)28-8-5-6-9-29(28)32-37-38-39-40(32)2/h5-6,8-19,21,23H,3-4,7,20,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284678
(CHEMBL281453 | Thiophene-2-carboxylic acid {3-[2'-...)Show SMILES CCCCCN(C(=O)c1cccs1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C33H31N7O2S/c1-3-4-7-18-40(33(42)30-11-8-19-43-30)25-16-17-29-28(20-25)32(41)39(22-34-29)21-23-12-14-24(15-13-23)26-9-5-6-10-27(26)31-35-36-37-38(31)2/h5-6,8-17,19-20,22H,3-4,7,18,21H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284654
(CHEMBL29725 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccncc2)cc1 Show InChI InChI=1S/C35H27N9O2/c1-42-33(39-40-41-42)30-8-3-2-7-29(30)25-11-9-24(10-12-25)21-43-23-38-32-14-13-28(20-31(32)35(43)46)44(22-27-6-4-5-17-37-27)34(45)26-15-18-36-19-16-26/h2-20,23H,21-22H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284673
(CHEMBL29658 | Furan-2-carboxylic acid {3-[2'-(1-me...)Show SMILES CCCCCN(C(=O)c1ccco1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C33H31N7O3/c1-3-4-7-18-40(33(42)30-11-8-19-43-30)25-16-17-29-28(20-25)32(41)39(22-34-29)21-23-12-14-24(15-13-23)26-9-5-6-10-27(26)31-35-36-37-38(31)2/h5-6,8-17,19-20,22H,3-4,7,18,21H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284677
(CHEMBL29063 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetra...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccncc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-10-6-5-9-30(31)27-13-11-26(12-14-27)22-43-24-38-33-16-15-29(21-32(33)36(43)46)44(23-25-7-3-2-4-8-25)35(45)28-17-19-37-20-18-28/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284641
(4-[(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES COC(=O)c1ccc(CN(C(=O)c2ccccc2)c2ccc3ncn(Cc4ccc(cc4)-c4ccccc4-c4nnnn4C)c(=O)c3c2)cc1 Show InChI InChI=1S/C39H31N7O4/c1-44-36(41-42-43-44)33-11-7-6-10-32(33)28-16-12-26(13-17-28)23-45-25-40-35-21-20-31(22-34(35)38(45)48)46(37(47)29-8-4-3-5-9-29)24-27-14-18-30(19-15-27)39(49)50-2/h3-22,25H,23-24H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/B
(RAT) | BDBM50284662
(CHEMBL281890 | DiSodium salt; Phosphoric acid mono...)Show SMILES CCCCN(C(=O)c1ccc(OP([O-])([O-])=O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H32N7O6P/c1-3-4-19-41(33(42)25-13-16-27(17-14-25)47-48(44,45)46)26-15-18-31-30(20-26)34(43)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22H,3-4,19,21H2,1-2H3,(H2,44,45,46)/p-2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rat adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284663
(CHEMBL282168 | N-Butyl-4-hydroxy-N-{3-[2'-(1-methy...)Show SMILES CCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H31N7O3/c1-3-4-19-41(33(43)25-13-16-27(42)17-14-25)26-15-18-31-30(20-26)34(44)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22,42H,3-4,19,21H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284654
(CHEMBL29725 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccncc2)cc1 Show InChI InChI=1S/C35H27N9O2/c1-42-33(39-40-41-42)30-8-3-2-7-29(30)25-11-9-24(10-12-25)21-43-23-38-32-14-13-28(20-31(32)35(43)46)44(22-27-6-4-5-17-37-27)34(45)26-15-18-36-19-16-26/h2-20,23H,21-22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284676
(CHEMBL29734 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES CCCCCN(C(=O)c1cccnc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H32N8O2/c1-3-4-7-19-42(33(43)26-9-8-18-35-21-26)27-16-17-31-30(20-27)34(44)41(23-36-31)22-24-12-14-25(15-13-24)28-10-5-6-11-29(28)32-37-38-39-40(32)2/h5-6,8-18,20-21,23H,3-4,7,19,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284645
(CHEMBL29512 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetra...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O2/c1-42-35(39-40-41-42)32-15-9-8-14-31(32)28-18-16-27(17-19-28)23-43-25-38-34-21-20-30(22-33(34)37(43)46)44(24-26-10-4-2-5-11-26)36(45)29-12-6-3-7-13-29/h2-22,25H,23-24H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284649
(4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284655
(CHEMBL30015 | N-(4-Hydroxy-benzyl)-N-{3-[2'-(1-met...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccc(O)cc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O3/c1-42-35(39-40-41-42)32-10-6-5-9-31(32)27-15-11-25(12-16-27)22-43-24-38-34-20-17-29(21-33(34)37(43)47)44(23-26-13-18-30(45)19-14-26)36(46)28-7-3-2-4-8-28/h2-21,24,45H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284661
(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284671
(CHEMBL29020 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccncc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-10-6-5-9-30(31)27-13-11-25(12-14-27)22-43-24-38-33-16-15-29(21-32(33)36(43)46)44(23-26-17-19-37-20-18-26)35(45)28-7-3-2-4-8-28/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284655
(CHEMBL30015 | N-(4-Hydroxy-benzyl)-N-{3-[2'-(1-met...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccc(O)cc2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H29N7O3/c1-42-35(39-40-41-42)32-10-6-5-9-31(32)27-15-11-25(12-16-27)22-43-24-38-34-20-17-29(21-33(34)37(43)47)44(23-26-13-18-30(45)19-14-26)36(46)28-7-3-2-4-8-28/h2-21,24,45H,22-23H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284665
(4-Methylsulfanyl-N-{3-[2'-(1-methyl-1H-tetrazol-5-...)Show SMILES CCCCCN(C(=O)c1ccc(SC)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H35N7O2S/c1-4-5-8-21-43(35(44)27-15-18-29(46-3)19-16-27)28-17-20-33-32(22-28)36(45)42(24-37-33)23-25-11-13-26(14-12-25)30-9-6-7-10-31(30)34-38-39-40-41(34)2/h6-7,9-20,22,24H,4-5,8,21,23H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284666
(4-[(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccc(cc2)C(O)=O)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C38H29N7O4/c1-43-35(40-41-42-43)32-10-6-5-9-31(32)27-15-11-25(12-16-27)22-44-24-39-34-20-19-30(21-33(34)37(44)47)45(36(46)28-7-3-2-4-8-28)23-26-13-17-29(18-14-26)38(48)49/h2-21,24H,22-23H2,1H3,(H,48,49) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284661
(CHEMBL30086 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-13-6-5-12-30(31)26-16-14-25(15-17-26)22-43-24-38-33-19-18-29(21-32(33)36(43)46)44(23-28-11-7-8-20-37-28)35(45)27-9-3-2-4-10-27/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284646
(4-Methanesulfonyl-N-{3-[2'-(1-methyl-1H-tetrazol-5...)Show SMILES CCCCCN(C(=O)c1ccc(cc1)S(C)(=O)=O)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H35N7O4S/c1-4-5-8-21-43(35(44)27-15-18-29(19-16-27)48(3,46)47)28-17-20-33-32(22-28)36(45)42(24-37-33)23-25-11-13-26(14-12-25)30-9-6-7-10-31(30)34-38-39-40-41(34)2/h6-7,9-20,22,24H,4-5,8,21,23H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284650
(CHEMBL280988 | Furan-2-carboxylic acid {3-[2'-(1-m...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccco2)cc1 Show InChI InChI=1S/C34H26N8O3/c1-40-32(37-38-39-40)28-9-3-2-8-27(28)24-13-11-23(12-14-24)20-41-22-36-30-16-15-26(19-29(30)33(41)43)42(21-25-7-4-5-17-35-25)34(44)31-10-6-18-45-31/h2-19,22H,20-21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284650
(CHEMBL280988 | Furan-2-carboxylic acid {3-[2'-(1-m...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccco2)cc1 Show InChI InChI=1S/C34H26N8O3/c1-40-32(37-38-39-40)28-9-3-2-8-27(28)24-13-11-23(12-14-24)20-41-22-36-30-16-15-26(19-29(30)33(41)43)42(21-25-7-4-5-17-35-25)34(44)31-10-6-18-45-31/h2-19,22H,20-21H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284668
(4-Benzyloxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-b...)Show SMILES CCCCCN(C(=O)c1ccc(OCc2ccccc2)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C42H39N7O3/c1-3-4-10-25-49(41(50)33-19-22-35(23-20-33)52-28-31-11-6-5-7-12-31)34-21-24-39-38(26-34)42(51)48(29-43-39)27-30-15-17-32(18-16-30)36-13-8-9-14-37(36)40-44-45-46-47(40)2/h5-9,11-24,26,29H,3-4,10,25,27-28H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284652
(CHEMBL281891 | Pyridine-2-carboxylic acid benzyl-{...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2ccccn2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)30-12-6-5-11-29(30)27-16-14-26(15-17-27)22-43-24-38-32-19-18-28(21-31(32)35(43)45)44(23-25-9-3-2-4-10-25)36(46)33-13-7-8-20-37-33/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284675
(4-(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biph...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(CCCC(O)=O)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C34H29N7O4/c1-39-32(36-37-38-39)28-11-6-5-10-27(28)24-15-13-23(14-16-24)21-40-22-35-30-18-17-26(20-29(30)34(40)45)41(19-7-12-31(42)43)33(44)25-8-3-2-4-9-25/h2-6,8-11,13-18,20,22H,7,12,19,21H2,1H3,(H,42,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284641
(4-[(Benzoyl-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...)Show SMILES COC(=O)c1ccc(CN(C(=O)c2ccccc2)c2ccc3ncn(Cc4ccc(cc4)-c4ccccc4-c4nnnn4C)c(=O)c3c2)cc1 Show InChI InChI=1S/C39H31N7O4/c1-44-36(41-42-43-44)33-11-7-6-10-32(33)28-16-12-26(13-17-28)23-45-25-40-35-21-20-31(22-34(35)38(45)48)46(37(47)29-8-4-3-5-9-29)24-27-14-18-30(19-15-27)39(49)50-2/h3-22,25H,23-24H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284654
(CHEMBL29725 | N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccn2)C(=O)c2ccncc2)cc1 Show InChI InChI=1S/C35H27N9O2/c1-42-33(39-40-41-42)30-8-3-2-7-29(30)25-11-9-24(10-12-25)21-43-23-38-32-14-13-28(20-31(32)35(43)46)44(22-27-6-4-5-17-37-27)34(45)26-15-18-36-19-16-26/h2-20,23H,21-22H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284669
(CHEMBL279756 | N-Benzyl-N-{3-[2'-(1-methyl-1H-tetr...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2ccccc2)C(=O)c2cccnc2)cc1 Show InChI InChI=1S/C36H28N8O2/c1-42-34(39-40-41-42)31-12-6-5-11-30(31)27-15-13-26(14-16-27)22-43-24-38-33-18-17-29(20-32(33)36(43)46)44(23-25-8-3-2-4-9-25)35(45)28-10-7-19-37-21-28/h2-21,24H,22-23H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284679
(CHEMBL108190 | N-(2-Furan-2-yl-2-oxo-ethyl)-N-{3-[...)Show SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(CC(=O)c2ccco2)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C36H27N7O4/c1-41-34(38-39-40-41)29-11-6-5-10-28(29)25-15-13-24(14-16-25)21-42-23-37-31-18-17-27(20-30(31)36(42)46)43(22-32(44)33-12-7-19-47-33)35(45)26-8-3-2-4-9-26/h2-20,23H,21-22H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284659
(6-(Benzyl-pentyl-amino)-3-[2'-(1-methyl-1H-tetrazo...)Show SMILES CCCCCN(Cc1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H35N7O/c1-3-4-10-21-41(23-26-11-6-5-7-12-26)29-19-20-33-32(22-29)35(43)42(25-36-33)24-27-15-17-28(18-16-27)30-13-8-9-14-31(30)34-37-38-39-40(34)2/h5-9,11-20,22,25H,3-4,10,21,23-24H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50284662
(CHEMBL281890 | DiSodium salt; Phosphoric acid mono...)Show SMILES CCCCN(C(=O)c1ccc(OP([O-])([O-])=O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H32N7O6P/c1-3-4-19-41(33(42)25-13-16-27(17-14-25)47-48(44,45)46)26-15-18-31-30(20-26)34(43)40(22-35-31)21-23-9-11-24(12-10-23)28-7-5-6-8-29(28)32-36-37-38-39(32)2/h5-18,20,22H,3-4,19,21H2,1-2H3,(H2,44,45,46)/p-2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in human adrenal tissue |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284657
(4-Methanesulfinyl-N-{3-[2'-(1-methyl-1H-tetrazol-5...)Show SMILES CCCCCN(C(=O)c1ccc(cc1)S(C)=O)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C36H35N7O3S/c1-4-5-8-21-43(35(44)27-15-18-29(19-16-27)47(3)46)28-17-20-33-32(22-28)36(45)42(24-37-33)23-25-11-13-26(14-12-25)30-9-6-7-10-31(30)34-38-39-40-41(34)2/h6-7,9-20,22,24H,4-5,8,21,23H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50284670
(Butane-1-sulfonic acid benzyl-{3-[2'-(1-methyl-1H-...)Show SMILES CCCCS(=O)(=O)N(Cc1ccccc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C34H33N7O3S/c1-3-4-20-45(43,44)41(23-25-10-6-5-7-11-25)28-18-19-32-31(21-28)34(42)40(24-35-32)22-26-14-16-27(17-15-26)29-12-8-9-13-30(29)33-36-37-38-39(33)2/h5-19,21,24H,3-4,20,22-23H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against AT1 receptor in rabbit aorta |
Bioorg Med Chem Lett 5: 1359-1364 (1995)
Article DOI: 10.1016/0960-894X(95)00224-H
BindingDB Entry DOI: 10.7270/Q2086589 |
More data for this
Ligand-Target Pair | |
Search and Browse
