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Articleid 50029819

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50049041
PNG
(5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-s...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CC2(CC2)C1)c1ccc(F)cc1 |t:11|
Show InChI InChI=1S/C20H19FO2S/c1-24(22,23)17-8-4-15(5-9-17)19-13-20(10-11-20)12-18(19)14-2-6-16(21)7-3-14/h2-9H,10-13H2,1H3
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n/an/a 1.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288289
PNG
(1-Methanesulfonyl-4-(3-methylene-2-phenyl-cyclobut...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=C)C1)c1ccccc1 |t:11|
Show InChI InChI=1S/C18H16O2S/c1-13-12-17(18(13)15-6-4-3-5-7-15)14-8-10-16(11-9-14)21(2,19)20/h3-11H,1,12H2,2H3
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n/an/a 1.20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50029600
PNG
(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
Show InChI InChI=1S/C17H12BrFO2S2/c1-23(20,21)14-8-4-11(5-9-14)15-10-16(18)22-17(15)12-2-6-13(19)7-3-12/h2-10H,1H3
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n/an/a 2.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288292
PNG
(1-(4,4-Dimethyl-3-methylene-2-phenyl-cyclobut-1-en...)
Show SMILES CC1(C)C(=C)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C20H20O2S/c1-14-18(15-8-6-5-7-9-15)19(20(14,2)3)16-10-12-17(13-11-16)23(4,21)22/h5-13H,1H2,2-4H3
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n/an/a 2.20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288291
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C19H18O3S/c1-19(2)17(14-9-11-15(12-10-14)23(3,21)22)16(18(19)20)13-7-5-4-6-8-13/h4-12H,1-3H3
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n/an/a 2.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288287
PNG
(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4...)
Show SMILES CC1(C)C(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1 |c:5|
Show InChI InChI=1S/C19H17FO3S/c1-19(2)17(13-6-10-15(11-7-13)24(3,22)23)16(18(19)21)12-4-8-14(20)9-5-12/h4-11H,1-3H3
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n/an/a 5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288294
PNG
(3-(4-Methanesulfonyl-phenyl)-2-phenyl-spiro[3.4]oc...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C11CCCC1)c1ccccc1 |t:11|
Show InChI InChI=1S/C21H20O3S/c1-25(23,24)17-11-9-16(10-12-17)19-18(15-7-3-2-4-8-15)20(22)21(19)13-5-6-14-21/h2-4,7-12H,5-6,13-14H2,1H3
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n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM17638
PNG
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
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n/an/a 39n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM17638
PNG
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
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n/an/a 49n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50029600
PNG
(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
Show InChI InChI=1S/C17H12BrFO2S2/c1-23(20,21)14-8-4-11(5-9-14)15-10-16(18)22-17(15)12-2-6-13(19)7-3-12/h2-10H,1H3
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n/an/a 59n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288293
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(N=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:6|
Show InChI InChI=1S/C19H19NO3S/c1-19(2)17(14-9-11-15(12-10-14)24(3,22)23)16(18(19)20-21)13-7-5-4-6-8-13/h4-12,18H,1-3H3
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n/an/a 61n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288290
PNG
(2-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-3-phenyl...)
Show SMILES CC1(C)C(=O)C(=C1c1ccccc1)c1ccc(cc1)S(C)(=O)=O |c:5|
Show InChI InChI=1S/C19H18O3S/c1-19(2)17(14-7-5-4-6-8-14)16(18(19)20)13-9-11-15(12-10-13)23(3,21)22/h4-12H,1-3H3
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n/an/a 96n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288288
PNG
(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclobut-2-e...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C1)c1ccccc1 |t:11|
Show InChI InChI=1S/C17H14O3S/c1-21(19,20)14-9-7-12(8-10-14)15-11-16(18)17(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 110n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288292
PNG
(1-(4,4-Dimethyl-3-methylene-2-phenyl-cyclobut-1-en...)
Show SMILES CC1(C)C(=C)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C20H20O2S/c1-14-18(15-8-6-5-7-9-15)19(20(14,2)3)16-10-12-17(13-11-16)23(4,21)22/h5-13H,1H2,2-4H3
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n/an/a 120n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50049041
PNG
(5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-s...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CC2(CC2)C1)c1ccc(F)cc1 |t:11|
Show InChI InChI=1S/C20H19FO2S/c1-24(22,23)17-8-4-15(5-9-17)19-13-20(10-11-20)12-18(19)14-2-6-16(21)7-3-14/h2-9H,10-13H2,1H3
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n/an/a 140n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288287
PNG
(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4...)
Show SMILES CC1(C)C(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1 |c:5|
Show InChI InChI=1S/C19H17FO3S/c1-19(2)17(13-6-10-15(11-7-13)24(3,22)23)16(18(19)21)12-4-8-14(20)9-5-12/h4-11H,1-3H3
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n/an/a 370n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288294
PNG
(3-(4-Methanesulfonyl-phenyl)-2-phenyl-spiro[3.4]oc...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C11CCCC1)c1ccccc1 |t:11|
Show InChI InChI=1S/C21H20O3S/c1-25(23,24)17-11-9-16(10-12-17)19-18(15-7-3-2-4-8-15)20(22)21(19)13-5-6-14-21/h2-4,7-12H,5-6,13-14H2,1H3
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n/an/a 500n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288295
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C19H20O3S/c1-19(2)17(14-9-11-15(12-10-14)23(3,21)22)16(18(19)20)13-7-5-4-6-8-13/h4-12,18,20H,1-3H3
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n/an/a 530n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288289
PNG
(1-Methanesulfonyl-4-(3-methylene-2-phenyl-cyclobut...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=C)C1)c1ccccc1 |t:11|
Show InChI InChI=1S/C18H16O2S/c1-13-12-17(18(13)15-6-4-3-5-7-15)14-8-10-16(11-9-14)21(2,19)20/h3-11H,1,12H2,2H3
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n/an/a 540n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288291
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C19H18O3S/c1-19(2)17(14-9-11-15(12-10-14)23(3,21)22)16(18(19)20)13-7-5-4-6-8-13/h4-12H,1-3H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288290
PNG
(2-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-3-phenyl...)
Show SMILES CC1(C)C(=O)C(=C1c1ccccc1)c1ccc(cc1)S(C)(=O)=O |c:5|
Show InChI InChI=1S/C19H18O3S/c1-19(2)17(14-7-5-4-6-8-14)16(18(19)20)13-9-11-15(12-10-13)23(3,21)22/h4-12H,1-3H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288288
PNG
(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclobut-2-e...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C1)c1ccccc1 |t:11|
Show InChI InChI=1S/C17H14O3S/c1-21(19,20)14-9-7-12(8-10-14)15-11-16(18)17(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 4.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50288296
PNG
(1-Methanesulfonyl-4-(2-phenyl-cyclobut-1-enyl)-ben...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CC1)c1ccccc1 |t:11|
Show InChI InChI=1S/C17H16O2S/c1-20(18,19)15-9-7-14(8-10-15)17-12-11-16(17)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3
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n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288293
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(N=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:6|
Show InChI InChI=1S/C19H19NO3S/c1-19(2)17(14-9-11-15(12-10-14)24(3,22)23)16(18(19)20-21)13-7-5-4-6-8-13/h4-12,18H,1-3H3
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n/an/a 3.40E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))		BDBM50288295
PNG
(3-(4-Methanesulfonyl-phenyl)-4,4-dimethyl-2-phenyl...)
Show SMILES CC1(C)C(O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccccc1 |c:5|
Show InChI InChI=1S/C19H20O3S/c1-19(2)17(14-9-11-15(12-10-14)23(3,21)22)16(18(19)20)13-7-5-4-6-8-13/h4-12,18,20H,1-3H3
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n/an/a 4.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1

Bioorg Med Chem Lett 6: 2677-2682 (1996)


Article DOI: 10.1016/S0960-894X(96)00501-X
BindingDB Entry DOI: 10.7270/Q2RB74M8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%