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PubMed code 7650684

Compile data set for download or QSAR
Found 39 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24185
PNG
((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)
Show SMILES CP(O)(=O)CCCN
Show InChI InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7)
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n/an/a 0.0160n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24184
PNG
((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)
Show SMILES NCCCP(O)=O
Show InChI InChI=1S/C3H10NO2P/c4-2-1-3-7(5)6/h7H,1-4H2,(H,5,6)
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n/an/a 2.40n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24184
PNG
((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)
Show SMILES NCCCP(O)=O
Show InChI InChI=1S/C3H10NO2P/c4-2-1-3-7(5)6/h7H,1-4H2,(H,5,6)
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n/an/a 5.40n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24185
PNG
((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)
Show SMILES CP(O)(=O)CCCN
Show InChI InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7)
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n/an/a 6.60n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032964
PNG
((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Show SMILES NC[C@H](CC(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1
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n/an/a 15n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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n/an/a 17n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24186
PNG
((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Show SMILES NCC(=O)CP(O)O
Show InChI InChI=1S/C3H8NO3P/c4-1-3(5)2-8(6)7/h6-7H,1-2,4H2
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n/an/a 18n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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n/an/a 25n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24189
PNG
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Show SMILES CP(O)(O)CC(=O)CN
Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3
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n/an/a 29n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to cat Gamma-aminobutyric acid type B receptor


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032964
PNG
((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)
Show SMILES NC[C@H](CC(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1
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n/an/a 32n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM24182
PNG
(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
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n/an/a 35n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032958
PNG
(CHEMBL430501 | [3-Amino-2-(4-chloro-phenyl)-propyl...)
Show SMILES NCC(CP(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C9H13ClNO2P/c10-9-3-1-7(2-4-9)8(5-11)6-14(12)13/h1-4,8,14H,5-6,11H2,(H,12,13)
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n/an/a 39n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24189
PNG
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Show SMILES CP(O)(O)CC(=O)CN
Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3
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n/an/a 45n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24189
PNG
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Show SMILES CP(O)(O)CC(=O)CN
Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3
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n/an/a 45n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032969
PNG
(CHEMBL321255 | [3-Amino-2-(4-chloro-phenyl)-2-hydr...)
Show SMILES NCC(O)(CP(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C9H13ClNO3P/c10-8-3-1-7(2-4-8)9(12,5-11)6-15(13)14/h1-4,12,15H,5-6,11H2,(H,13,14)
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n/an/a 65n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032968
PNG
((3-Amino-propyl)-difluoromethyl-phosphinic acid | ...)
Show SMILES NCCCP(O)(=O)C(F)F
Show InChI InChI=1S/C4H10F2NO2P/c5-4(6)10(8,9)3-1-2-7/h4H,1-3,7H2,(H,8,9)
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n/an/a 89n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24182
PNG
(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
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n/an/a 107n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032971
PNG
((3-Amino-1-methyl-propyl)-methyl-phosphinic acid |...)
Show SMILES CC(CCN)P(C)(O)=O
Show InChI InChI=1S/C5H14NO2P/c1-5(3-4-6)9(2,7)8/h5H,3-4,6H2,1-2H3,(H,7,8)
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n/an/a 140n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM24189
PNG
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Show SMILES CP(O)(O)CC(=O)CN
Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3
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n/an/a 152n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032971
PNG
((3-Amino-1-methyl-propyl)-methyl-phosphinic acid |...)
Show SMILES CC(CCN)P(C)(O)=O
Show InChI InChI=1S/C5H14NO2P/c1-5(3-4-6)9(2,7)8/h5H,3-4,6H2,1-2H3,(H,7,8)
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n/an/a 166n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to cat Gamma-aminobutyric acid type B receptor


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032961
PNG
((3-Amino-2-hydroxy-propyl)-difluoromethyl-phosphin...)
Show SMILES NCC(=O)CP(O)(O)C(F)F
Show InChI InChI=1S/C4H10F2NO3P/c5-4(6)11(9,10)2-3(8)1-7/h4,9-11H,1-2,7H2
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n/an/a 213n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032962
PNG
(((Z)-3-Amino-propenyl)-phosphinic acid | CGP38593 ...)
Show SMILES NCCCP(=O)=O
Show InChI InChI=1S/C3H8NO2P/c4-2-1-3-7(5)6/h1-4H2
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n/an/a 280n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032959
PNG
(CHEMBL111378 | [3-Amino-2-(4-fluoro-phenyl)-propyl...)
Show SMILES NCC(CP(O)=O)c1ccc(F)cc1
Show InChI InChI=1S/C9H13FNO2P/c10-9-3-1-7(2-4-9)8(5-11)6-14(12)13/h1-4,8,14H,5-6,11H2,(H,12,13)
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n/an/a 360n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032970
PNG
((3-Amino-butyl)-phosphinic acid | CHEMBL113907)
Show SMILES CC(N)CCP(O)=O
Show InChI InChI=1S/C4H12NO2P/c1-4(5)2-3-8(6)7/h4,8H,2-3,5H2,1H3,(H,6,7)
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n/an/a 500n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032973
PNG
(((Z)-3-Amino-propenyl)-methyl-phosphinic acid | 3-...)
Show SMILES CP(O)(=O)CCC=N
Show InChI InChI=1S/C4H10NO2P/c1-8(6,7)4-2-3-5/h3,5H,2,4H2,1H3,(H,6,7)
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n/an/a 665n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032975
PNG
((3-Amino-2-methyl-propyl)-phosphinic acid | CHEMBL...)
Show SMILES CC(CN)CP(O)=O
Show InChI InChI=1S/C4H12NO2P/c1-4(2-5)3-8(6)7/h4,8H,2-3,5H2,1H3,(H,6,7)
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n/an/a 780n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032977
PNG
((3-Amino-2-phenyl-propyl)-phosphinic acid | CHEMBL...)
Show SMILES NCC(CP(O)=O)c1ccccc1
Show InChI InChI=1S/C9H14NO2P/c10-6-9(7-13(11)12)8-4-2-1-3-5-8/h1-5,9,13H,6-7,10H2,(H,11,12)
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n/an/a 880n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032967
PNG
((3-Amino-1-methyl-propyl)-phosphinic acid | CHEMBL...)
Show SMILES CC(CCN)P(O)=O
Show InChI InChI=1S/C4H12NO2P/c1-4(2-3-5)8(6)7/h4,8H,2-3,5H2,1H3,(H,6,7)
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n/an/a 920n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032979
PNG
((3-Amino-propyl)-hydroxymethyl-phosphinic acid | C...)
Show SMILES NCCCP(O)(O)C=O
Show InChI InChI=1S/C4H12NO3P/c5-2-1-3-9(7,8)4-6/h4,7-9H,1-3,5H2
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n/an/a 1.05E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032966
PNG
((3-Amino-1-hydroxy-propyl)-methyl-phosphinic acid ...)
Show SMILES CP(O)(O)C(=O)CCN
Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)4(6)2-3-5/h7-9H,2-3,5H2,1H3
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n/an/a 1.16E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032972
PNG
((3-Amino-propyl)-ethyl-phosphinic acid | CGP-36216...)
Show SMILES CCP(O)(=O)CCCN
Show InChI InChI=1S/C5H14NO2P/c1-2-9(7,8)5-3-4-6/h2-6H2,1H3,(H,7,8)
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n/an/a 1.35E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032963
PNG
((S)-4-Amino-3-(4-chloro-phenyl)-butyric acid | BAC...)
Show SMILES NC[C@@H](CC(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m1/s1
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n/an/a 1.77E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032972
PNG
((3-Amino-propyl)-ethyl-phosphinic acid | CGP-36216...)
Show SMILES CCP(O)(=O)CCCN
Show InChI InChI=1S/C5H14NO2P/c1-2-9(7,8)5-3-4-6/h2-6H2,1H3,(H,7,8)
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n/an/a 1.98E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032962
PNG
(((Z)-3-Amino-propenyl)-phosphinic acid | CGP38593 ...)
Show SMILES NCCCP(=O)=O
Show InChI InChI=1S/C3H8NO2P/c4-2-1-3-7(5)6/h1-4H2
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n/an/a 4.41E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032981
PNG
((3-Amino-propyl)-phosphonic acid | CHEMBL286077 | ...)
Show SMILES NCCCP(O)(O)=O
Show InChI InChI=1S/C3H10NO3P/c4-2-1-3-8(5,6)7/h1-4H2,(H2,5,6,7)
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n/an/a 6.81E+3n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Homo sapiens (Human))
BDBM50032965
PNG
(((R)-3-Amino-2-hydroxy-butyl)-phosphinic acid | CH...)
Show SMILES C[C@@H](N)C(=O)CP(O)O
Show InChI InChI=1S/C4H10NO3P/c1-3(5)4(6)2-9(7)8/h3,7-8H,2,5H2,1H3/t3-/m1/s1
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n/an/a 1.28E+4n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032973
PNG
(((Z)-3-Amino-propenyl)-methyl-phosphinic acid | 3-...)
Show SMILES CP(O)(=O)CCC=N
Show InChI InChI=1S/C4H10NO2P/c1-8(6,7)4-2-3-5/h3,5H,2,4H2,1H3,(H,6,7)
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n/an/a 1.66E+4n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032974
PNG
((3-Amino-1-ethyl-propyl)-methyl-phosphinic acid | ...)
Show SMILES CCC(CCN)P(C)(O)=O
Show InChI InChI=1S/C6H16NO2P/c1-3-6(4-5-7)10(2,8)9/h6H,3-5,7H2,1-2H3,(H,8,9)
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n/an/a 1.85E+4n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2


(Rattus norvegicus (Rat))
BDBM50032960
PNG
((3-Amino-1-trifluoromethyl-propyl)-methyl-phosphin...)
Show SMILES CP(O)(=O)C(CCN)C(F)(F)F
Show InChI InChI=1S/C5H11F3NO2P/c1-12(10,11)4(2-3-9)5(6,7)8/h4H,2-3,9H2,1H3,(H,10,11)
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n/an/a 6.76E+4n/an/an/an/an/an/a



CIBA-GEIGY AG

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortex


J Med Chem 38: 3297-312 (1995)


BindingDB Entry DOI: 10.7270/Q2N58KDP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%