Affinity Data by PubMed id=8809168

PubMed code 8809168

Found 31 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053297 (1-{4-[2-(1H-Imidazol-4-yl)-ethoxy]-phenyl}-propan-...) Show SMILES CCC(=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 \| N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50033042 (2-[2-(1H-Imidazol-4-yl)-ethylsulfanyl]-5-nitro-pyr...) Show SMILES [O-][N+](=O)c1ccc(SCCc2cnc[nH]2)nc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053275 (4-[2-(1H-Imidazol-4-yl)-ethoxy]-benzoic acid methy...) Show SMILES COC(=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053281 (4-[2-(1H-Imidazol-4-yl)-ethoxy]-benzoic acid ethyl...) Show SMILES CCOC(=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053289 (4-[2-(1H-Imidazol-4-yl)-ethoxy]-benzonitrile \| CHE...) Show SMILES N#Cc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053273 (4-[2-(4-Nitro-phenylsulfanyl)-ethyl]-1H-imidazole ...) Show SMILES [O-][N+](=O)c1ccc(SCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053274 (4-[3-(4-Fluoro-phenoxy)-propyl]-1H-imidazole \| CHE...) Show SMILES Fc1ccc(OCCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053290 (4-[2-(3-Nitro-phenoxy)-ethyl]-1H-imidazole \| CHEMB...) Show SMILES [O-][N+](=O)c1cccc(OCCc2cnc[nH]2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053278 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzonitrile \| 4-...) Show SMILES N#Cc1ccc(OCCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053298 (4-[3-(4-Trifluoromethyl-phenoxy)-propyl]-1H-imidaz...) Show SMILES FC(F)(F)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053288 (4-[2-(4-Propyl-phenoxy)-ethyl]-1H-imidazole \| CHEM...) Show SMILES CCCc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50033036 (CHEMBL419574 \| [2-(1H-Imidazol-4-yl)-ethyl]-(5-nit...) Show SMILES [O-][N+](=O)c1ccc(NCCc2cnc[nH]2)nc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053294 (4-[2-(4-Chloro-phenoxy)-ethyl]-1H-imidazole \| CHEM...) Show SMILES Clc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053280 (CHEMBL435383 \| [2-(1H-Imidazol-4-yl)-ethyl]-(4-nit...) Show SMILES [O-][N+](=O)c1ccc(NCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053292 (1-{4-[2-(1H-Imidazol-4-yl)-ethoxy]-phenyl}-ethanon...) Show SMILES CC(=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053277 (4-[2-(4-Bromo-phenoxy)-ethyl]-1H-imidazole \| CHEMB...) Show SMILES Brc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053279 (4-[2-(4-Nitro-phenoxy)-ethyl]-1H-imidazole \| CHEMB...) Show SMILES [O-][N+](=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053271 (4-[2-(4-Methoxy-phenoxy)-ethyl]-1H-imidazole \| CHE...) Show SMILES COc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053282 (3-[2-(1H-Imidazol-4-yl)-ethoxy]-benzonitrile \| CHE...) Show SMILES N#Cc1cccc(OCCc2cnc[nH]2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053295 (CHEMBL125751 \| {4-[2-(1H-Imidazol-4-yl)-ethoxy]-ph...) Show SMILES O=C(c1ccccc1)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053272 (4-(2-p-Tolyloxy-ethyl)-1H-imidazole \| CHEMBL125947) Show SMILES Cc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053284 (4-[2-(4-Trifluoromethyl-phenoxy)-ethyl]-1H-imidazo...) Show SMILES FC(F)(F)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053285 (4-[2-(4-Ethyl-phenoxy)-ethyl]-1H-imidazole \| CHEMB...) Show SMILES CCc1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053276 (4-[2-(Naphthalen-2-yloxy)-ethyl]-1H-imidazole \| CH...) Show SMILES C(Cc1cnc[nH]1)Oc1ccc2ccccc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053296 (4-[2-(Naphthalen-1-yloxy)-ethyl]-1H-imidazole \| CH...) Show SMILES C(Cc1cnc[nH]1)Oc1cccc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053287 (4-(4-Nitro-benzylsulfanylmethyl)-1H-imidazole \| CH...) Show SMILES [O-][N+](=O)c1ccc(CSCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	313	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053293 (CHEMBL339606 \| {4-[2-(1H-Imidazol-4-yl)-ethoxy]-ph...) Show SMILES O=C(N1CCCCC1)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053283 (2-[2-(1H-Imidazol-4-yl)-ethoxy]-benzonitrile \| CHE...) Show SMILES N#Cc1ccccc1OCCc1cnc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	483	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053291 (4-[2-(3,5-Dichloro-phenoxy)-ethyl]-1H-imidazole \| ...) Show SMILES Clc1cc(Cl)cc(OCCc2cnc[nH]2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053286 (4-(2-Pentafluorophenyloxy-ethyl)-1H-imidazole \| CH...) Show SMILES Fc1c(F)c(F)c(OCCc2cnc[nH]2)c(F)c1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
University College London Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%