Affinity Data by PubMed id=9767631

PubMed code 9767631

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50054124 (1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCN3CCCC(C)(C)C3)CCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0890	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50054124 (1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCN3CCCC(C)(C)C3)CCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0890	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067018 (1-[5-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2C(CCCCCN3CCCC(C)(C)C3)CCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50054121 (3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES CC1(C)CCCN(CCCCC2CCCc3ccccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067019 (1-[3-(3H-Inden-1-yl)-propyl]-3,3-dimethyl-piperidi...) Show SMILES CC1(C)CCCN(CCCC2=CCc3ccccc23)C1 \|t:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067010 (1-(3-Indan-1-yl-propyl)-3,3-dimethyl-piperidine \| ...) Show SMILES CC1(C)CCCN(CCCC2CCc3ccccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067012 (1-[4-(4-Methoxy-indan-1-yl)-butyl]-3,3-dimethyl-pi...) Show SMILES COc1cccc2C(CCCCN3CCCC(C)(C)C3)CCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067008 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCCC(C)(C)C3)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067016 (1-[4-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCCN3CCCC(C)(C)C3)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067014 (5-[3-(3,3-Dimethyl-piperidin-1-yl)-propyl]-5,6,7,8...) Show SMILES CC1(C)CCCN(CCCC2CCCc3c(O)cccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067011 (3,3-Dimethyl-1-[3-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES CC1(C)CCCN(CCCC2CCCc3ccccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067013 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCCC(C)(C)C3)CCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	978	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067015 (3,3-Dimethyl-1-[5-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES CC1(C)CCCN(CCCCCC2CCCc3ccccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067020 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCCC(C)(C)C3)CCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067022 (1-[3-(5-Methoxy-indan-1-yl)-propyl]-3,3-dimethyl-p...) Show SMILES COc1ccc2C(CCCN3CCCC(C)(C)C3)CCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067017 (3,3-Dimethyl-1-(5-phenyl-pentyl)-piperidine \| CHEM...) Show SMILES CC1(C)CCCN(CCCCCc2ccccc2)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067021 (1-[4-(3,4-Dihydro-naphthalen-1-yl)-butyl]-3,3-dime...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067023 (1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCN3CCCC(C)(C)C3)CCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50067009 (3,3-Dimethyl-1-[2-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES CC1(C)CCCN(CCC2CCCc3ccccc23)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.				J Med Chem 41: 3940-7 (1998) Article DOI: 10.1021/jm970692a BindingDB Entry DOI: 10.7270/Q2NK3D5Q
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%