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PubMed code 9873567

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071664
PNG
(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Br2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 32n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071667
PNG
(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Cl)c(O)c(Cl)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Cl2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 102n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071666
PNG
(2-(3,5-Dibromo-4-hydroxy-benzylidene)-5,6-dimethox...)
Show SMILES [#6]-[#8]-c1cc2-[#6](=O)\[#6](=[#6]\c3cc(Br)c(-[#8])c(Br)c3)-[#6](=O)-c2cc1-[#8]-[#6]
Show InChI InChI=1S/C18H12Br2O5/c1-24-14-6-9-10(7-15(14)25-2)17(22)11(16(9)21)3-8-4-12(19)18(23)13(20)5-8/h3-7,23H,1-2H3
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n/an/a 110n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071677
PNG
(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Show SMILES COc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C17H10Br2O4/c1-23-9-2-3-10-11(7-9)16(21)12(15(10)20)4-8-5-13(18)17(22)14(19)6-8/h2-7,22H,1H3/b12-4+
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n/an/a 144n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071668
PNG
(2-(3,5-Dichloro-4-hydroxy-benzylidene)-5,6-dimetho...)
Show SMILES [#6]-[#8]-c1cc2-[#6](=O)\[#6](=[#6]\c3cc(Cl)c(-[#8])c(Cl)c3)-[#6](=O)-c2cc1-[#8]-[#6]
Show InChI InChI=1S/C18H12Cl2O5/c1-24-14-6-9-10(7-15(14)25-2)17(22)11(16(9)21)3-8-4-12(19)18(23)13(20)5-8/h3-7,23H,1-2H3
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n/an/a 310n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50071664
PNG
(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Br2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 460n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Src tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071676
PNG
(4-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1cccc2C(=O)\C(=C\c3cc(Br)c(O)c(Br)c3)C(=O)c12
Show InChI InChI=1S/C16H9Br2NO3/c17-10-5-7(6-11(18)16(10)22)4-9-14(20)8-2-1-3-12(19)13(8)15(9)21/h1-6,22H,19H2/b9-4-
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n/an/a 470n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071665
PNG
(5-Amino-2-[1-(3,4-dihydroxy-phenyl)-meth-(E)-ylide...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3ccc(O)c(O)c3)C(=O)c2c1
Show InChI InChI=1S/C16H11NO4/c17-9-2-3-10-11(7-9)16(21)12(15(10)20)5-8-1-4-13(18)14(19)6-8/h1-7,18-19H,17H2/b12-5+
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n/an/a 600n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071670
PNG
(6-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1ccc2C\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C16H11Br2NO2/c17-13-4-8(5-14(18)16(13)21)3-10-6-9-1-2-11(19)7-12(9)15(10)20/h1-5,7,21H,6,19H2/b10-3+
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n/an/a 710n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071669
PNG
(2-(3,5-Dibromo-4-hydroxy-benzylidene)-indan-1,3-di...)
Show SMILES [#8]-c1c(Br)cc(\[#6]=[#6]-2\[#6](=O)-c3ccccc3-[#6]-2=O)cc1Br
Show InChI InChI=1S/C16H8Br2O3/c17-12-6-8(7-13(18)16(12)21)5-11-14(19)9-3-1-2-4-10(9)15(11)20/h1-7,21H
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n/an/a 740n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071682
PNG
(2-[1-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-meth-(E)...)
Show SMILES COc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(OC)c3)C(=O)c2c1
Show InChI InChI=1S/C18H13BrO5/c1-23-10-3-4-11-12(8-10)17(21)13(16(11)20)5-9-6-14(19)18(22)15(7-9)24-2/h3-8,22H,1-2H3/b13-5+
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n/an/a 880n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071678
PNG
(5-Bromo-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Oc1c(Br)cc(\C=C2/C(=O)c3ccc(Br)cc3C2=O)cc1Br
Show InChI InChI=1S/C16H7Br3O3/c17-8-1-2-9-10(6-8)15(21)11(14(9)20)3-7-4-12(18)16(22)13(19)5-7/h1-6,22H/b11-3+
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n/an/a 1.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071675
PNG
(2-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Show SMILES Oc1c(Cl)cc(\C=C2\C(=O)c3cccc(c3C2=O)[N+]([O-])=O)cc1Cl
Show InChI InChI=1S/C16H7Cl2NO5/c17-10-5-7(6-11(18)16(10)22)4-9-14(20)8-2-1-3-12(19(23)24)13(8)15(9)21/h1-6,22H/b9-4-
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n/an/a 1.40E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071681
PNG
(2-[1-(3,4-Dihydroxy-phenyl)-meth-(E)-ylidene]-5-me...)
Show SMILES COc1ccc2C(=O)\C(=C/c3ccc(O)c(O)c3)C(=O)c2c1
Show InChI InChI=1S/C17H12O5/c1-22-10-3-4-11-12(8-10)17(21)13(16(11)20)6-9-2-5-14(18)15(19)7-9/h2-8,18-19H,1H3/b13-6+
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n/an/a 1.50E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071673
PNG
(5-Amino-2-[1-(4-hydroxy-3,5-dimethoxy-phenyl)-meth...)
Show SMILES COc1cc(\C=C2/C(=O)c3ccc(N)cc3C2=O)cc(OC)c1O
Show InChI InChI=1S/C18H15NO5/c1-23-14-6-9(7-15(24-2)18(14)22)5-13-16(20)11-4-3-10(19)8-12(11)17(13)21/h3-8,22H,19H2,1-2H3/b13-5+
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n/an/a 1.70E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071680
PNG
(2-(3-Bromo-4-hydroxy-5-methoxy-benzylidene)-5,6-di...)
Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6]-2/[#6](=O)-c3cc(Cl)c(Cl)cc3-[#6]-2=O)cc(Br)c1-[#8]
Show InChI InChI=1S/C17H9BrCl2O4/c1-24-14-4-7(3-11(18)17(14)23)2-10-15(21)8-5-12(19)13(20)6-9(8)16(10)22/h2-6,23H,1H3
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n/an/a 1.70E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50071667
PNG
(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Cl)c(O)c(Cl)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Cl2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 3.50E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Src tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma


(Homo sapiens (Human))		BDBM50071667
PNG
(5-Amino-2-[1-(3,5-dichloro-4-hydroxy-phenyl)-meth-...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Cl)c(O)c(Cl)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Cl2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Protein Kinase A (PKA)

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071674
PNG
(2-[1-(3,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-5-ni...)
Show SMILES Oc1ccc(\C=C2\C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc1O
Show InChI InChI=1S/C16H9NO6/c18-13-4-1-8(6-14(13)19)5-12-15(20)10-3-2-9(17(22)23)7-11(10)16(12)21/h1-7,18-19H/b12-5-
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n/an/a>5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071671
PNG
(5,6-Dichloro-2-(4-hydroxy-3-methoxy-benzylidene)-i...)
Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6]-2\[#6](=O)-c3cc(Cl)c(Cl)cc3-[#6]-2=O)ccc1-[#8]
Show InChI InChI=1S/C17H10Cl2O4/c1-23-15-5-8(2-3-14(15)20)4-11-16(21)9-6-12(18)13(19)7-10(9)17(11)22/h2-7,20H,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071683
PNG
(2-[1-(3,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-4-ni...)
Show SMILES Oc1ccc(\C=C2\C(=O)c3cccc(c3C2=O)[N+]([O-])=O)cc1O
Show InChI InChI=1S/C16H9NO6/c18-12-5-4-8(7-13(12)19)6-10-15(20)9-2-1-3-11(17(22)23)14(9)16(10)21/h1-7,18-19H/b10-6-
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071672
PNG
(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Show SMILES Oc1c(Br)cc(\C=C2/C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc1Br
Show InChI InChI=1S/C16H7Br2NO5/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19(23)24)6-10(9)15(11)21/h1-6,22H/b11-3+
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n/an/a>5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50071679
PNG
(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1ccc2C(=O)\C(Cc2c1)=C\c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C16H11Br2NO2/c17-13-4-8(5-14(18)16(13)21)3-10-6-9-7-11(19)1-2-12(9)15(10)20/h1-5,7,21H,6,19H2/b10-3+
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50067024
PNG
(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Show SMILES [#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-c3ccccc3-[#6]-2=O)cc1-[#8]
Show InChI InChI=1S/C16H10O4/c17-13-6-5-9(8-14(13)18)7-12-15(19)10-3-1-2-4-11(10)16(12)20/h1-8,17-18H
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50045936
PNG
((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Show SMILES Oc1cc(O)cc(\C=C\c2ccc(O)c(O)c2)c1
Show InChI InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+
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n/an/a 5.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma


(Homo sapiens (Human))		BDBM50071664
PNG
(5-Amino-2-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Show SMILES Nc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C16H9Br2NO3/c17-12-4-7(5-13(18)16(12)22)3-11-14(20)9-2-1-8(19)6-10(9)15(11)21/h1-6,22H,19H2/b11-3+
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n/an/a 8.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Protein Kinase A (PKA)

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma


(Homo sapiens (Human))		BDBM50071677
PNG
(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Show SMILES COc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C17H10Br2O4/c1-23-9-2-3-10-11(7-9)16(21)12(15(10)20)4-8-5-13(18)17(22)14(19)6-8/h2-7,22H,1H3/b12-4+
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n/an/a 1.00E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Protein Kinase A (PKA)

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50071677
PNG
(2-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(E)-ylide...)
Show SMILES COc1ccc2C(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)C(=O)c2c1
Show InChI InChI=1S/C17H10Br2O4/c1-23-9-2-3-10-11(7-9)16(21)12(15(10)20)4-8-5-13(18)17(22)14(19)6-8/h2-7,22H,1H3/b12-4+
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n/an/a>5.00E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Src tyrosine kinase

Bioorg Med Chem Lett 8: 2489-94 (1999)


BindingDB Entry DOI: 10.7270/Q2D50M3V
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%