BindingDB logo
myBDB logout

PubMed code 9888831

Compile data set for download or QSAR
Found 83 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069258
PNG
(3-Benzhydrylidene-1-{4-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H32FN3O2/c32-26-13-15-27(16-14-26)34-21-19-33(20-22-34)17-7-8-18-35-29(36)23-28(31(35)37)30(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-16H,7-8,17-23H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.30n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072893
PNG
(3-Benzhydrylidene-1-{4-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]C#C[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H31N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-9,12-17H,18-24H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 6.60n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072880
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C32H33N3O3/c1-38-29-15-7-6-14-28(29)34-20-18-33(19-21-34)16-8-9-17-35-30(36)22-27(32(35)37)31-25-12-4-2-10-23(25)24-11-3-5-13-26(24)31/h2-7,10-15H,8-9,16-22H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069249
PNG
(3-Benzhydrylidene-1-{4-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H35N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-9,12-17H,10-11,18-24H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072891
PNG
(3-Fluoren-9-ylidene-1-[4-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1/c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C31H31N3O2/c35-29-22-28(30-26-14-6-4-12-24(26)25-13-5-7-15-27(25)30)31(36)34(29)17-9-8-16-32-18-20-33(21-19-32)23-10-2-1-3-11-23/h1-7,10-15H,8-9,16-22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069260
PNG
(3-Benzhydrylidene-1-{4-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H32F3N3O2/c33-32(34,35)26-14-9-15-27(22-26)37-20-18-36(19-21-37)16-7-8-17-38-29(39)23-28(31(38)40)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 15n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072882
PNG
(3-Benzhydrylidene-1-{(E)-4-[4-(2-methoxy-phenyl)-p...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6]\[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H33N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-17H,18-24H2,1H3/b11-10+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 27n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072876
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H31N3O3/c1-37-28-14-7-6-13-27(28)33-19-17-32(18-20-33)15-8-16-34-29(35)21-26(31(34)36)30-24-11-4-2-9-22(24)23-10-3-5-12-25(23)30/h2-7,9-14H,8,15-21H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 37n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM59418
PNG
(1-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-3-(d...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H32ClN3O2/c32-26-14-9-15-27(22-26)34-20-18-33(19-21-34)16-7-8-17-35-29(36)23-28(31(35)37)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 39n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072872
PNG
(1-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-3-flu...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C28H24ClN3O2/c29-19-6-5-7-20(16-19)31-14-12-30(13-15-31)18-32-26(33)17-25(28(32)34)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 42n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069250
PNG
(3-Benzhydrylidene-1-[4-(3-chloro-phenyl)-piperazin...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C28H26ClN3O2/c29-23-12-7-13-24(18-23)31-16-14-30(15-17-31)20-32-26(33)19-25(28(32)34)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 49n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069257
PNG
(3-Benzhydrylidene-1-[4-(3-trifluoromethyl-phenyl)-...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26F3N3O2/c30-29(31,32)23-12-7-13-24(18-23)34-16-14-33(15-17-34)20-35-26(36)19-25(28(35)37)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 59n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072878
PNG
(3-Fluoren-9-ylidene-1-[4-(2-methoxy-phenyl)-pipera...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H27N3O3/c1-35-26-13-7-6-12-25(26)31-16-14-30(15-17-31)19-32-27(33)18-24(29(32)34)28-22-10-4-2-8-20(22)21-9-3-5-11-23(21)28/h2-13H,14-19H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 61n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072874
PNG
(1-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-3...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30ClN3O2/c32-22-8-7-9-23(20-22)34-18-16-33(17-19-34)14-5-6-15-35-29(36)21-28(31(35)37)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 72n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069262
PNG
(3-Benzhydrylidene-1-[4-(2-methoxy-phenyl)-piperazi...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H29N3O3/c1-35-26-15-9-8-14-25(26)31-18-16-30(17-19-31)21-32-27(33)20-24(29(32)34)28(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15H,16-21H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 93n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069266
PNG
(3-Benzhydrylidene-1-(4-phenyl-piperazin-1-ylmethyl...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](\c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C28H27N3O2/c32-26-20-25(27(22-10-4-1-5-11-22)23-12-6-2-7-13-23)28(33)31(26)21-29-16-18-30(19-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 98n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072877
PNG
(3-Fluoren-9-ylidene-1-[4-(3-trifluoromethyl-phenyl...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H24F3N3O2/c30-29(31,32)19-6-5-7-20(16-19)34-14-12-33(13-15-34)18-35-26(36)17-25(28(35)37)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 114n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069261
PNG
(3-Benzhydrylidene-1-[4-(4-phenyl-piperazin-1-yl)-b...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C31H33N3O2/c35-29-24-28(30(25-12-4-1-5-13-25)26-14-6-2-7-15-26)31(36)34(29)19-11-10-18-32-20-22-33(23-21-32)27-16-8-3-9-17-27/h1-9,12-17H,10-11,18-24H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 125n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069264
PNG
(3-Benzhydrylidene-1-{3-[4-(3-chloro-phenyl)-pipera...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H30ClN3O2/c31-25-13-7-14-26(21-25)33-19-17-32(18-20-33)15-8-16-34-28(35)22-27(30(34)36)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 127n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069254
PNG
(3-Benzhydrylidene-1-{3-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H33N3O3/c1-37-28-16-9-8-15-27(28)33-21-19-32(20-22-33)17-10-18-34-29(35)23-26(31(34)36)30(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16H,10,17-23H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 156n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069256
PNG
(3-Benzhydrylidene-1-{2-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H31N3O3/c1-36-27-15-9-8-14-26(27)32-19-16-31(17-20-32)18-21-33-28(34)22-25(30(33)35)29(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15H,16-22H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 167n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072884
PNG
(3-Fluoren-9-ylidene-1-(4-phenyl-piperazin-1-ylmeth...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1/c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C28H25N3O2/c32-26-18-25(27-23-12-6-4-10-21(23)22-11-5-7-13-24(22)27)28(33)31(26)19-29-14-16-30(17-15-29)20-8-2-1-3-9-20/h1-13H,14-19H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 201n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072890
PNG
(3-Benzhydrylidene-1-{(Z)-4-[4-(2-methoxy-phenyl)-p...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6]/[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H33N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-17H,18-24H2,1H3/b11-10-
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 237n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069256
PNG
(3-Benzhydrylidene-1-{2-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H31N3O3/c1-36-27-15-9-8-14-26(27)32-19-16-31(17-20-32)18-21-33-28(34)22-25(30(33)35)29(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15H,16-22H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 286n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069258
PNG
(3-Benzhydrylidene-1-{4-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H32FN3O2/c32-26-13-15-27(16-14-26)34-21-19-33(20-22-34)17-7-8-18-35-29(36)23-28(31(35)37)30(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-16H,7-8,17-23H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 351n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM59418
PNG
(1-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-3-(d...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H32ClN3O2/c32-26-14-9-15-27(22-26)34-20-18-33(19-21-34)16-7-8-17-35-29(36)23-28(31(35)37)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 367n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072891
PNG
(3-Fluoren-9-ylidene-1-[4-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1/c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C31H31N3O2/c35-29-22-28(30-26-14-6-4-12-24(26)25-13-5-7-15-27(25)30)31(36)34(29)17-9-8-16-32-18-20-33(21-19-32)23-10-2-1-3-11-23/h1-7,10-15H,8-9,16-22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 397n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069254
PNG
(3-Benzhydrylidene-1-{3-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H33N3O3/c1-37-28-16-9-8-15-27(28)33-21-19-32(20-22-33)17-10-18-34-29(35)23-26(31(34)36)30(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16H,10,17-23H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 665n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069260
PNG
(3-Benzhydrylidene-1-{4-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H32F3N3O2/c33-32(34,35)26-14-9-15-27(22-26)37-20-18-36(19-21-37)16-7-8-17-38-29(39)23-28(31(38)40)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 689n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069264
PNG
(3-Benzhydrylidene-1-{3-[4-(3-chloro-phenyl)-pipera...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H30ClN3O2/c31-25-13-7-14-26(21-25)33-19-17-32(18-20-33)15-8-16-34-28(35)22-27(30(34)36)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 801n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069259
PNG
(3-Benzhydrylidene-1-{3-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30F3N3O2/c32-31(33,34)25-13-7-14-26(21-25)36-19-17-35(18-20-36)15-8-16-37-28(38)22-27(30(37)39)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069262
PNG
(3-Benzhydrylidene-1-[4-(2-methoxy-phenyl)-piperazi...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H29N3O3/c1-35-26-15-9-8-14-25(26)31-18-16-30(17-19-31)21-32-27(33)20-24(29(32)34)28(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15H,16-21H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069263
PNG
(3-Benzhydrylidene-1-[2-(4-phenyl-piperazin-1-yl)-e...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](\c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C29H29N3O2/c33-27-22-26(28(23-10-4-1-5-11-23)24-12-6-2-7-13-24)29(34)32(27)21-18-30-16-19-31(20-17-30)25-14-8-3-9-15-25/h1-15H,16-22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072871
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H29N3O3/c1-36-27-13-7-6-12-26(27)32-17-14-31(15-18-32)16-19-33-28(34)20-25(30(33)35)29-23-10-4-2-8-21(23)22-9-3-5-11-24(22)29/h2-13H,14-20H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072887
PNG
(3-Fluoren-9-ylidene-1-[3-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1\c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C30H29N3O2/c34-28-21-27(29-25-13-6-4-11-23(25)24-12-5-7-14-26(24)29)30(35)33(28)16-8-15-31-17-19-32(20-18-31)22-9-2-1-3-10-22/h1-7,9-14H,8,15-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072879
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H28F3N3O2/c32-31(33,34)21-7-5-8-22(19-21)36-17-15-35(16-18-36)13-6-14-37-28(38)20-27(30(37)39)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069257
PNG
(3-Benzhydrylidene-1-[4-(3-trifluoromethyl-phenyl)-...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26F3N3O2/c30-29(31,32)23-12-7-13-24(18-23)34-16-14-33(15-17-34)20-35-26(36)19-25(28(35)37)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072876
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H31N3O3/c1-37-28-14-7-6-13-27(28)33-19-17-32(18-20-33)15-8-16-34-29(35)21-26(31(34)36)30-24-11-4-2-9-22(24)23-10-3-5-12-25(23)30/h2-7,9-14H,8,15-21H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069261
PNG
(3-Benzhydrylidene-1-[4-(4-phenyl-piperazin-1-yl)-b...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C31H33N3O2/c35-29-24-28(30(25-12-4-1-5-13-25)26-14-6-2-7-15-26)31(36)34(29)19-11-10-18-32-20-22-33(23-21-32)27-16-8-3-9-17-27/h1-9,12-17H,10-11,18-24H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072888
PNG
(1-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28ClN3O2/c31-21-7-5-8-22(19-21)33-17-15-32(16-18-33)13-6-14-34-28(35)20-27(30(34)36)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069249
PNG
(3-Benzhydrylidene-1-{4-[4-(2-methoxy-phenyl)-piper...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C32H35N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-9,12-17H,10-11,18-24H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069267
PNG
(3-Benzhydrylidene-1-[4-(4-fluoro-phenyl)-piperazin...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C28H26FN3O2/c29-23-11-13-24(14-12-23)31-17-15-30(16-18-31)20-32-26(33)19-25(28(32)34)27(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14H,15-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069268
PNG
(3-Benzhydrylidene-1-{3-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H30FN3O2/c31-25-12-14-26(15-13-25)33-20-18-32(19-21-33)16-7-17-34-28(35)22-27(30(34)36)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15H,7,16-22H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069263
PNG
(3-Benzhydrylidene-1-[2-(4-phenyl-piperazin-1-yl)-e...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](\c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C29H29N3O2/c33-27-22-26(28(23-10-4-1-5-11-23)24-12-6-2-7-13-24)29(34)32(27)21-18-30-16-19-31(20-17-30)25-14-8-3-9-15-25/h1-15H,16-22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072883
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C32H30F3N3O2/c33-32(34,35)22-8-7-9-23(20-22)37-18-16-36(17-19-37)14-5-6-15-38-29(39)21-28(31(38)40)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069266
PNG
(3-Benzhydrylidene-1-(4-phenyl-piperazin-1-ylmethyl...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](\c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C28H27N3O2/c32-26-20-25(27(22-10-4-1-5-11-22)23-12-6-2-7-13-23)28(33)31(26)21-29-16-18-30(19-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072883
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C32H30F3N3O2/c33-32(34,35)22-8-7-9-23(20-22)37-18-16-36(17-19-37)14-5-6-15-38-29(39)21-28(31(38)40)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072892
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28FN3O2/c31-21-10-12-22(13-11-21)33-18-16-32(17-19-33)14-5-15-34-28(35)20-27(30(34)36)29-25-8-3-1-6-23(25)24-7-2-4-9-26(24)29/h1-4,6-13H,5,14-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072887
PNG
(3-Fluoren-9-ylidene-1-[3-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1\c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C30H29N3O2/c34-28-21-27(29-25-13-6-4-11-23(25)24-12-5-7-14-26(24)29)30(35)33(28)16-8-15-31-17-19-32(20-18-31)22-9-2-1-3-10-22/h1-7,9-14H,8,15-21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069259
PNG
(3-Benzhydrylidene-1-{3-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30F3N3O2/c32-31(33,34)25-13-7-14-26(21-25)36-19-17-35(18-20-36)15-8-16-37-28(38)22-27(30(37)39)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069253
PNG
(3-Benzhydrylidene-1-{2-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28F3N3O2/c31-30(32,33)24-12-7-13-25(20-24)35-17-14-34(15-18-35)16-19-36-27(37)21-26(29(36)38)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069265
PNG
(3-Benzhydrylidene-1-[3-(4-phenyl-piperazin-1-yl)-p...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C30H31N3O2/c34-28-23-27(29(24-11-4-1-5-12-24)25-13-6-2-7-14-25)30(35)33(28)18-10-17-31-19-21-32(22-20-31)26-15-8-3-9-16-26/h1-9,11-16H,10,17-23H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069252
PNG
(3-Benzhydrylidene-1-{2-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H28FN3O2/c30-24-11-13-25(14-12-24)32-18-15-31(16-19-32)17-20-33-27(34)21-26(29(33)35)28(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14H,15-21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069268
PNG
(3-Benzhydrylidene-1-{3-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H30FN3O2/c31-25-12-14-26(15-13-25)33-20-18-32(19-21-33)16-7-17-34-28(35)22-27(30(34)36)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15H,7,16-22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069253
PNG
(3-Benzhydrylidene-1-{2-[4-(3-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28F3N3O2/c31-30(32,33)24-12-7-13-25(20-24)35-17-14-34(15-18-35)16-19-36-27(37)21-26(29(36)38)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069252
PNG
(3-Benzhydrylidene-1-{2-[4-(4-fluoro-phenyl)-pipera...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H28FN3O2/c30-24-11-13-25(14-12-24)32-18-15-31(16-19-32)17-20-33-27(34)21-26(29(33)35)28(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14H,15-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069251
PNG
(3-Benzhydrylidene-1-{2-[4-(3-chloro-phenyl)-pipera...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H28ClN3O2/c30-24-12-7-13-25(20-24)32-17-14-31(15-18-32)16-19-33-27(34)21-26(29(33)35)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069250
PNG
(3-Benzhydrylidene-1-[4-(3-chloro-phenyl)-piperazin...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C28H26ClN3O2/c29-23-12-7-13-24(18-23)31-16-14-30(15-17-31)20-32-26(33)19-25(28(32)34)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069251
PNG
(3-Benzhydrylidene-1-{2-[4-(3-chloro-phenyl)-pipera...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C29H28ClN3O2/c30-24-12-7-13-25(20-24)32-17-14-31(15-18-32)16-19-33-27(34)21-26(29(33)35)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50069267
PNG
(3-Benzhydrylidene-1-[4-(4-fluoro-phenyl)-piperazin...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](\c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1
Show InChI InChI=1S/C28H26FN3O2/c29-23-11-13-24(14-12-23)31-17-15-30(16-18-31)20-32-26(33)19-25(28(32)34)27(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14H,15-20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072874
PNG
(1-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-3...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30ClN3O2/c32-22-8-7-9-23(20-22)34-18-16-33(17-19-34)14-5-6-15-35-29(36)21-28(31(35)37)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072886
PNG
(3-Fluoren-9-ylidene-1-[4-(4-fluoro-phenyl)-piperaz...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C28H24FN3O2/c29-19-9-11-20(12-10-19)31-15-13-30(14-16-31)18-32-26(33)17-25(28(32)34)27-23-7-3-1-5-21(23)22-6-2-4-8-24(22)27/h1-12H,13-18H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072877
PNG
(3-Fluoren-9-ylidene-1-[4-(3-trifluoromethyl-phenyl...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H24F3N3O2/c30-29(31,32)19-6-5-7-20(16-19)34-14-12-33(13-15-34)18-35-26(36)17-25(28(35)37)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50069265
PNG
(3-Benzhydrylidene-1-[3-(4-phenyl-piperazin-1-yl)-p...)
Show SMILES O=[#6]-1-[#6]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1
Show InChI InChI=1S/C30H31N3O2/c34-28-23-27(29(24-11-4-1-5-12-24)25-13-6-2-7-14-25)30(35)33(28)18-10-17-31-19-21-32(22-20-31)26-15-8-3-9-16-26/h1-9,11-16H,10,17-23H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072892
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28FN3O2/c31-21-10-12-22(13-11-21)33-18-16-32(17-19-33)14-5-15-34-28(35)20-27(30(34)36)29-25-8-3-1-6-23(25)24-7-2-4-9-26(24)29/h1-4,6-13H,5,14-20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072873
PNG
(3-Fluoren-9-ylidene-1-[2-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1\c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C29H27N3O2/c33-27-20-26(28-24-12-6-4-10-22(24)23-11-5-7-13-25(23)28)29(34)32(27)19-16-30-14-17-31(18-15-30)21-8-2-1-3-9-21/h1-13H,14-20H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072872
PNG
(1-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-3-flu...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C28H24ClN3O2/c29-19-6-5-7-20(16-19)31-14-12-30(13-15-31)18-32-26(33)17-25(28(32)34)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072888
PNG
(1-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H28ClN3O2/c31-21-7-5-8-22(19-21)33-17-15-32(16-18-33)13-6-14-34-28(35)20-27(30(34)36)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072880
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C32H33N3O3/c1-38-29-15-7-6-14-28(29)34-20-18-33(19-21-34)16-8-9-17-35-30(36)22-27(32(35)37)31-25-12-4-2-10-23(25)24-11-3-5-13-26(24)31/h2-7,10-15H,8-9,16-22H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072875
PNG
(1-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26ClN3O2/c30-20-6-5-7-21(18-20)32-15-12-31(13-16-32)14-17-33-27(34)19-26(29(33)35)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072885
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30FN3O2/c32-22-11-13-23(14-12-22)34-19-17-33(18-20-34)15-5-6-16-35-29(36)21-28(31(35)37)30-26-9-3-1-7-24(26)25-8-2-4-10-27(25)30/h1-4,7-14H,5-6,15-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072889
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26FN3O2/c30-20-9-11-21(12-10-20)32-16-13-31(14-17-32)15-18-33-27(34)19-26(29(33)35)28-24-7-3-1-5-22(24)23-6-2-4-8-25(23)28/h1-12H,13-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072889
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26FN3O2/c30-20-9-11-21(12-10-20)32-16-13-31(14-17-32)15-18-33-27(34)19-26(29(33)35)28-24-7-3-1-5-22(24)23-6-2-4-8-25(23)28/h1-12H,13-19H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072885
PNG
(3-Fluoren-9-ylidene-1-{4-[4-(4-fluoro-phenyl)-pipe...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H30FN3O2/c32-22-11-13-23(14-12-22)34-19-17-33(18-20-34)15-5-6-16-35-29(36)21-28(31(35)37)30-26-9-3-1-7-24(26)25-8-2-4-10-27(25)30/h1-4,7-14H,5-6,15-21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072881
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H26F3N3O2/c31-30(32,33)20-6-5-7-21(18-20)35-15-12-34(13-16-35)14-17-36-27(37)19-26(29(36)38)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072881
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H26F3N3O2/c31-30(32,33)20-6-5-7-21(18-20)35-15-12-34(13-16-35)14-17-36-27(37)19-26(29(36)38)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072878
PNG
(3-Fluoren-9-ylidene-1-[4-(2-methoxy-phenyl)-pipera...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H27N3O3/c1-35-26-13-7-6-12-25(26)31-16-14-30(15-17-31)19-32-27(33)18-24(29(32)34)28-22-10-4-2-8-20(22)21-9-3-5-11-23(21)28/h2-13H,14-19H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50072875
PNG
(1-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Show SMILES Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C29H26ClN3O2/c30-20-6-5-7-21(18-20)32-15-12-31(13-16-32)14-17-33-27(34)19-26(29(33)35)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072871
PNG
(3-Fluoren-9-ylidene-1-{2-[4-(2-methoxy-phenyl)-pip...)
Show SMILES [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C30H29N3O3/c1-36-27-13-7-6-12-26(27)32-17-14-31(15-18-32)16-19-33-28(34)20-25(30(33)35)29-23-10-4-2-8-21(23)22-9-3-5-11-24(22)29/h2-13H,14-20H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072884
PNG
(3-Fluoren-9-ylidene-1-(4-phenyl-piperazin-1-ylmeth...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1/c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C28H25N3O2/c32-26-18-25(27-23-12-6-4-10-21(23)22-11-5-7-13-24(22)27)28(33)31(26)19-29-14-16-30(17-15-29)20-8-2-1-3-9-20/h1-13H,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072873
PNG
(3-Fluoren-9-ylidene-1-[2-(4-phenyl-piperazin-1-yl)...)
Show SMILES O=[#6]-1-[#6]\[#6](-[#6](=O)-[#7]-1-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ccccc1)=[#6]-1\c2ccccc2-c2ccccc-12
Show InChI InChI=1S/C29H27N3O2/c33-27-20-26(28-24-12-6-4-10-22(24)23-11-5-7-13-25(23)28)29(34)32(27)19-16-30-14-17-31(18-15-30)21-8-2-1-3-9-21/h1-13H,14-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072879
PNG
(3-Fluoren-9-ylidene-1-{3-[4-(3-trifluoromethyl-phe...)
Show SMILES FC(F)(F)c1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2/c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C31H28F3N3O2/c32-31(33,34)21-7-5-8-22(19-21)36-17-15-35(16-18-36)13-6-14-37-28(38)20-27(30(37)39)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50072886
PNG
(3-Fluoren-9-ylidene-1-[4-(4-fluoro-phenyl)-piperaz...)
Show SMILES Fc1ccc(cc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1
Show InChI InChI=1S/C28H24FN3O2/c29-19-9-11-20(12-10-19)31-15-13-30(14-16-31)18-32-26(33)17-25(28(32)34)27-23-7-3-1-5-21(23)22-6-2-4-8-24(22)27/h1-12H,13-18H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Dopamine receptor D2 of rat striatal membranes using [3H]- raclopride

J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%