Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125050 (US8772511, 11 | US9714242, 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | -49.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125053 (US8772511, 22) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | <1 | <-47.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125047 (US8772511, 4 | US9714242, 22) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.10 | -46.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125052 (US8772511, 21 | US9714242, 21) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.30 | -44.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125049 (US8772511, 6 | US9714242, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 7.90 | -43.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125051 (US8772511, 16 | US9714242, 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 15 | -41.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM125048 (US8772511, 5 | US9714242, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 22 | -40.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair |