Reaction Details | |||
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Target | Tyrosine-protein kinase Mer | ||
Ligand | BDBM336487 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
IC50 | <10±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein kinase Mer | |||
Name: | Tyrosine-protein kinase Mer | ||
Synonyms: | MER | MER intracellular domain/EGFR extracellular domain chimera | MERTK | MERTK_HUMAN | Proto-oncogene c-Mer | Proto-oncogene tyrosine-protein kinase MER | Receptor tyrosine kinase MerTK | Tyrosine-protein kinase Mer | ||
Type: | PROTEIN | ||
Mol. Mass.: | 110234.77 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1498723 | ||
Residue: | 999 | ||
Sequence: |
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BDBM336487 | |||
n/a | |||
Name | BDBM336487 | ||
Synonyms: | US9744172, Compound UNC1315A | ||
Type | Small organic molecule | ||
Emp. Form. | C33H43N7O5S | ||
Mol. Mass. | 649.803 | ||
SMILES | CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N(C)c1ccc(cc1)C(=O)NCCCOC |r,wD:15.15,(-10.57,-7.54,;-9.23,-6.77,;-7.9,-7.54,;-6.57,-6.77,;-5.23,-7.54,;-3.9,-6.77,;-3.9,-5.23,;-2.57,-4.46,;-1.23,-5.23,;.23,-4.76,;1.14,-6,;.23,-7.25,;.63,-8.74,;2.12,-9.14,;2.52,-10.62,;1.43,-11.71,;1.83,-13.2,;-.06,-11.31,;-.46,-9.83,;-1.23,-6.77,;-2.57,-7.54,;.63,-3.27,;2.12,-2.87,;2.52,-1.38,;1.43,-.29,;-.06,-.69,;-.46,-2.18,;1.83,1.19,;.29,1.19,;1.06,2.53,;3.31,1.59,;4.4,.5,;3.71,3.08,;5.2,3.48,;5.6,4.96,;4.51,6.05,;3.02,5.66,;2.62,4.17,;4.91,7.54,;3.82,8.63,;6.4,7.94,;6.8,9.43,;8.28,9.83,;8.68,11.31,;10.17,11.71,;10.57,13.2,)| | ||
Structure | ![]() |