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TargetCholecystokinin receptor type A
LigandBDBM50011542
Substrate/Competitorn/a
Meas. Tech.ChEBML_50182
IC50 26±n/a nM
Citation Tilley, JW; Danho, W; Lovey, K; Wagner, R; Swistok, J; Makofske, R; Michalewsky, J; Triscari, J; Nelson, D; Weatherford, S Carboxylic acids and tetrazoles as isosteric replacements for sulfate in cholecystokinin analogues. J Med Chem34:1125-36 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Cholecystokinin receptor type A
Name:Cholecystokinin receptor type A
Synonyms:CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:Enzyme Catalytic Domain
Mol. Mass.:49676.37
Organism:RAT
Description:Cholecystokinin central 0 RAT::P30551
Residue:444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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  Blast E-value cutoff:
BDBM50011542
n/a
NameBDBM50011542
Synonyms:3-[4-(carboxymethyl)phenyl]propanoyl-Met-Gly-Trp-Met-Asp-Phe-NH2 | CHEMBL273344
TypeSmall organic molecule
Emp. Form.C47H58N8O11S2
Mol. Mass.975.14
SMILESCSCC[C@H](NC(=O)CCc1ccc(CC(O)=O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure
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