| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon-like peptide 1 receptor |
|---|
| Ligand | BDBM50266693 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1717519 |
|---|
| EC50 | 7.7±n/a nM |
|---|
| Citation |  Zhou, J; Cai, X; Huang, X; Dai, Y; Sun, L; Zhang, B; Yang, B; Lin, H; Huang, W; Qian, H A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects. Eur J Med Chem138:1158-1169 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon-like peptide 1 receptor |
|---|
| Name: | Glucagon-like peptide 1 receptor |
|---|
| Synonyms: | GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53035.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43220 |
|---|
| Residue: | 463 |
|---|
| Sequence: | MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL
FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW
RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH
LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN
YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN
SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW
RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
|
|
|
|---|
| BDBM50266693 |
|---|
| n/a |
|---|
| Name | BDBM50266693 |
|---|
| Synonyms: | CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucagon Emergency Kit | Glucagon Recombinant |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C153H225N43O49S |
|---|
| Mol. Mass. | 3482.747 |
|---|
| SMILES | n/a |
|---|
| Structure | 
|
|---|
Search and Browse
