| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50468348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1799358 (CHEMBL4271650) |
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| EC50 | 631±n/a nM |
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| Citation |  Ge, X; Woo, AY; Xing, G; Lu, Y; Mo, Y; Zhao, Y; Lan, Y; Li, J; Yan, H; Pan, L; Zhang, Y; Lin, B; Cheng, M Synthesis and biological evaluation of ? Eur J Med Chem152:424-435 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50468348 |
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| n/a |
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| Name | BDBM50468348 |
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| Synonyms: | CHEMBL4285474 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24N2O3 |
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| Mol. Mass. | 400.4697 |
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| SMILES | OCC(NCC(c1ccccc1)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12 |
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| Structure | 
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