| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50468337 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1799359 (CHEMBL4271651) |
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| EC50 | 631±n/a nM |
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| Citation |  Ge, X; Woo, AY; Xing, G; Lu, Y; Mo, Y; Zhao, Y; Lan, Y; Li, J; Yan, H; Pan, L; Zhang, Y; Lin, B; Cheng, M Synthesis and biological evaluation of ? Eur J Med Chem152:424-435 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51338.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08588 |
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| Residue: | 477 |
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| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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| BDBM50468337 |
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| n/a |
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| Name | BDBM50468337 |
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| Synonyms: | CHEMBL4291941 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22N2O4 |
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| Mol. Mass. | 354.3997 |
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| SMILES | COc1cccc(CCNC(CO)c2ccc(O)c3[nH]c(=O)ccc23)c1 |
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| Structure | 
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