| Reaction Details |
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 | Report a problem with these data |
| Target | Protoporphyrinogen oxidase, chloroplastic |
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| Ligand | BDBM50488385 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_924308 (CHEMBL3081412) |
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| Ki | 210±n/a nM |
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| Citation |  Zuo, Y; Yang, SG; Luo, YP; Tan, Y; Hao, GF; Wu, QY; Xi, Z; Yang, GF Design and synthesis of 1-(benzothiazol-5-yl)-1H-1,2,4-triazol-5-ones as protoporphyrinogen oxidase inhibitors. Bioorg Med Chem21:3245-55 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protoporphyrinogen oxidase, chloroplastic |
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| Name: | Protoporphyrinogen oxidase, chloroplastic |
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| Synonyms: | 1.3.3.4 | PPO | PPO I | PPOC_TOBAC | PPX I | PPXI | Protoporphyrinogen IX oxidase isozyme I | Protoporphyrinogen oxidase, chloroplastic |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59244.44 |
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| Organism: | Nicotiana tabacum |
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| Description: | ChEMBL_106599 |
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| Residue: | 548 |
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| Sequence: | MTTTPIANHPNIFTHQSSSSPLAFLNRTSFIPFSSISKRNSVNCNGWRTRCSVAKDYTVP
SSAVDGGPAAELDCVIVGAGISGLCIAQVMSANYPNLMVTEARDRAGGNITTVERDGYLW
EEGPNSFQPSDPMLTMAVDCGLKDDLVLGDPNAPRFVLWKGKLRPVPSKLTDLAFFDLMS
IPGKLRAGFGAIGLRPSPPGHEESVEQFVRRNLGGEVFERLIEPFCSGVYAGDPSKLSMK
AAFGKVWKLEETGGSIIGGTFKAIKERSSTPKAPRDPRLPKPKGQTVGSFRKGLRMLPDA
ISARLGSKLKLSWKLSSITKSEKGGYHLTYETPEGVVSLQSRSIVMTVPSYVASNILRPL
SVAAADALSNFYYPPVGAVTITYPQEAIRDERLVDGELKGFGQLHPRTQGVETLGTIYSS
SLFPNRAPKGRVLLLNYIGGAKNPEILSKTESQLVEVVDRDLRKMLIKPKAQDPLVVGVR
VWPQAIPQFLVGHLDTLSTAKAAMNDNGLEGLFLGGNYVSGVALGRCVEGAYEVASEVTG
FLSRYAYK
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| BDBM50488385 |
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| n/a |
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| Name | BDBM50488385 |
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| Synonyms: | CHEMBL2286232 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15F3N4OS2 |
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| Mol. Mass. | 388.431 |
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| SMILES | CCCCSc1nc2cc(c(F)cc2s1)-n1nc(C)n(C(F)F)c1=O |
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| Structure | 
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