| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
|---|
| Ligand | BDBM50505275 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1822332 (CHEMBL4322096) |
|---|
| IC50 | 130±n/a nM |
|---|
| Citation |  Wu, G; Zhao, T; Kang, D; Zhang, J; Song, Y; Namasivayam, V; Kongsted, J; Pannecouque, C; De Clercq, E; Poongavanam, V; Liu, X; Zhan, P Overview of Recent Strategic Advances in Medicinal Chemistry. J Med Chem62:9375-9414 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Envelope glycoprotein gp160 |
|---|
| Name: | Envelope glycoprotein gp160 |
|---|
| Synonyms: | envelope glycoprotein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 91798.58 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | gi_45357394 |
|---|
| Residue: | 814 |
|---|
| Sequence: | MRVKGIRRNYQHLWRWGTMLLGMLMICSAKEQLWVTAYYGVPVWKEATTTLFCASDAKAY
DTEVHNVWATHACVPTDPNPREVVMGNVTEEFNIWNNSMVEQMHEDIISLWDESLKPCVK
LTPLCVTFNCTNYNGTRNGTTTEPPEVKNCTTKETGIKNCSFNIATSGVEDRFKKEYALL
YTADIVQIDNSSINYTLIGCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGK
GPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEVVIRSDNFSDNAKTIIVQLKDPVVINCT
RPNNNTRKGIRIGPGRTFYTTERIIGDIRQAHCNISRTQWNNTLRLIAAKLKKQFNNKTI
IFRNSSGGDPEIVMHSFNCGGEFFYCNTTQLFNSTWVHNNTWVHNNTGNDTEEGTITLPC
RIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLILTRDGGNTSSNNETFRPGGGDMRDN
WRSELYKYKVVKIEPLGVAPTKARRRVVQREKRAVGMLGAMFLGFLGAAGSTMGAASLAL
TVQARQVVSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLGDQQLLGIWG
CSGKLICTTAVPWNDSWSNKSLKYIWDNMTWMQWEKEIDIHVDTIYQLLEASQYQQEKNE
KDLLELDKWESLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSL
QTRLPTQRGPDRPEGIEEEGGERQRHIRSISEWILNNYPGRPAEPVPLQLPPLERLTLDC
NEDCGTSGTQGVGSPQVFVESPPVLESGTKEECC
|
|
|
|---|
| BDBM50505275 |
|---|
| n/a |
|---|
| Name | BDBM50505275 |
|---|
| Synonyms: | CHEMBL4573432 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H23N3O5 |
|---|
| Mol. Mass. | 457.4779 |
|---|
| SMILES | COc1ccc(-c2ccco2)c2[nH]cc(C(=O)C(=O)N3CCN(CC3)C(=O)c3ccccc3)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
