| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50070128 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_38801 |
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| EC50 | 1.3±n/a nM |
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| Citation |  Weber, AE; Ok, HO; Alvaro, RF; Candelore, MR; Cascieri, MA; Chiu, SH; Deng, L; Forrest, MJ; Hom, GJ; Hutchins, JE; Kao, J; MacIntyre, DE; Mathvink, RJ; McLoughlin, D; Miller, RR; Newbold, RC; Olah, TV; Parmee, ER; Perkins, L; Stearns, RA; Strader, CD; Szumiloski, J; Tang, YS; Tota, L; Fisher, MH 3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties. Bioorg Med Chem Lett8:2111-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50070128 |
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| n/a |
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| Name | BDBM50070128 |
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| Synonyms: | CHEMBL12769 | Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N3O5S |
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| Mol. Mass. | 493.575 |
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| SMILES | O[C@@H](CNCCc1ccc(NS(=O)(=O)c2cnc3ccccc3c2)cc1)COc1ccc(O)cc1 |
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| Structure | 
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