| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
|---|
| Ligand | BDBM50098553 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_226008 (CHEMBL842149) |
|---|
| Ki | 1950±n/a nM |
|---|
| Citation |  Enyedy, IJ; Lee, SL; Kuo, AH; Dickson, RB; Lin, CY; Wang, S Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase. J Med Chem44:1349-55 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urokinase-type plasminogen activator |
|---|
| Name: | Urokinase-type plasminogen activator |
|---|
| Synonyms: | 3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48528.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00749 |
|---|
| Residue: | 431 |
|---|
| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
|
|
|
|---|
| BDBM50098553 |
|---|
| n/a |
|---|
| Name | BDBM50098553 |
|---|
| Synonyms: | 4-(4-{4-[amino(imino)methyl]phenoxy}phenoxy)benzenecarboximidamide | CHEMBL26856 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H18N4O2 |
|---|
| Mol. Mass. | 346.3825 |
|---|
| SMILES | NC(=N)c1ccc(Oc2ccc(Oc3ccc(cc3)C(N)=N)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
