BindingDB PrimarySearch

Found 47 hits with Last Name = 'dickson' and Initial = 'rb'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypsin (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of Sunflower beta-trypsin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of Matriptase from human breast cancer cells				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin-3 (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of bovine beta trypsin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21737 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	-39.6	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21751 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	160	-38.4	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50098555 (4-[6-(4-Carbamimidoyl-phenoxy)-hexyloxy]-3-iodo-be...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50098553 (4-(4-{4-[amino(imino)methyl]phenoxy}phenoxy)benzen...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	208	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50015234 (4,4''[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDA...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Thrombin				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21750 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31S,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	380	-36.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21746 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	450	-35.9	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50098554 (4-(3-{4-[amino(imino)methyl]-2-bromophenoxy}propox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	535	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50098555 (4-[6-(4-Carbamimidoyl-phenoxy)-hexyloxy]-3-iodo-be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	796	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Thrombin				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21749 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	857	-34.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21739 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	860	-34.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21748 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	890	-34.2	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50015234 (4,4''[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDA...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	924	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50098554 (4-(3-{4-[amino(imino)methyl]-2-bromophenoxy}propox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	946	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Thrombin				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21747 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	-33.9	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098554 (4-(3-{4-[amino(imino)methyl]-2-bromophenoxy}propox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Urokinase-type plasminogen activator(microPa)				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098553 (4-(4-{4-[amino(imino)methyl]phenoxy}phenoxy)benzen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Urokinase-type plasminogen activator(microPa)				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50098555 (4-[6-(4-Carbamimidoyl-phenoxy)-hexyloxy]-3-iodo-be...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Urokinase-type plasminogen activator(microPa)				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21745 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.33E+3	-31.8	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50098553 (4-(4-{4-[amino(imino)methyl]phenoxy}phenoxy)benzen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Thrombin				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50098552 (1,5-Bis-[(4-amino(imino)methyl)phenyldiazeno]-anth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21739 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.75E+3	-30.1	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21737 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	-30.0	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of bovine Thrombin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21749 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.63E+3	-28.9	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21751 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	-28.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50098556 (4-(2-{4-[amino(imino)methyl]phenyl}ethyl)benzeneca...) Show SMILES NC(=N)c1ccc(CCc2ccc(cc2)C(N)=N)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Matriptase				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50015234 (4,4''[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDA...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description compound was tested for inhibitory activity against Urokinase-type plasminogen activator(microPa)				J Med Chem 44: 1349-55 (2001) BindingDB Entry DOI: 10.7270/Q2057F62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21746 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.63E+4	-27.1	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21742 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.25E+4	-26.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21747 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.56E+4	-25.9	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21743 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.80E+4	-25.7	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21748 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.36E+4	-25.3	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21744 (2-[(1S,7S,10S,13S,16S,22S,25S,31S,34S,37S,40S,43S,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.04E+4	-24.8	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21743 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.56E+4	-24.5	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21741 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.00E+4	-22.9	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21744 (2-[(1S,7S,10S,13S,16S,22S,25S,31S,34S,37S,40S,43S,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.07E+5	-22.4	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21741 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.64E+5	-21.4	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM21740 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>2.50E+5	>-20.4	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for microPa) Urokinase-type plasminogen activator from human urine				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21742 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.27E+5	-17.4	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21745 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>2.50E+6	>-14.7	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM21740 (2-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,40S,43S,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.5	22
Georgetown University Medical Center					Assay Description The enzyme reaction was initiated by adding fluorescence peptide substrate to reaction mixture containing enzyme and test compounds. The enzyme activ...				J Med Chem 50: 5976-83 (2007) Article DOI: 10.1021/jm0704898 BindingDB Entry DOI: 10.7270/Q2S75DNJ
Georgetown University Medical Center					More data for this Ligand-Target Pair