Reaction Details |
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Target | Prostaglandin E2 receptor EP2 subtype |
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Ligand | BDBM50117691 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_158305 |
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Ki | 590.0±n/a nM |
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Citation | Gallant, M; Carrière, MC; Chateauneuf, A; Denis, D; Gareau, Y; Godbout, C; Greig, G; Juteau, H; Lachance, N; Lacombe, P; Lamontagne, S; Metters, KM; Rochette, C; Ruel, R; Slipetz, D; Sawyer, N; Tremblay, N; Labelle, M Structure-activity relationship of biaryl acylsulfonamide analogues on the human EP(3) prostanoid receptor. Bioorg Med Chem Lett12:2583-6 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin E2 receptor EP2 subtype |
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Name: | Prostaglandin E2 receptor EP2 subtype |
Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
Type: | Enzyme |
Mol. Mass.: | 39775.71 |
Organism: | Homo sapiens (Human) |
Description: | P43116 |
Residue: | 358 |
Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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BDBM50117691 |
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n/a |
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Name | BDBM50117691 |
Synonyms: | CHEMBL86886 | Thiophene-2-sulfonic acid [2-(4'-phenethylsulfanylmethyl-biphenyl-2-yl)-acetyl]-amide |
Type | Small organic molecule |
Emp. Form. | C27H25NO3S3 |
Mol. Mass. | 507.687 |
SMILES | O=C(Cc1ccccc1-c1ccc(CSCCc2ccccc2)cc1)NS(=O)(=O)c1cccs1 |
Structure |
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