| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50117686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158305 |
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| Ki | 1800±n/a nM |
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| Citation |  Gallant, M; Carrière, MC; Chateauneuf, A; Denis, D; Gareau, Y; Godbout, C; Greig, G; Juteau, H; Lachance, N; Lacombe, P; Lamontagne, S; Metters, KM; Rochette, C; Ruel, R; Slipetz, D; Sawyer, N; Tremblay, N; Labelle, M Structure-activity relationship of biaryl acylsulfonamide analogues on the human EP(3) prostanoid receptor. Bioorg Med Chem Lett12:2583-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50117686 |
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| n/a |
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| Name | BDBM50117686 |
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| Synonyms: | CHEMBL445895 | Thiophene-2-sulfonic acid [4-(4'-phenethylsulfanylmethyl-biphenyl-2-yl)-butyryl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H29NO3S3 |
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| Mol. Mass. | 535.74 |
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| SMILES | O=C(CCCc1ccccc1-c1ccc(CSCCc2ccccc2)cc1)NS(=O)(=O)c1cccs1 |
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| Structure | 
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