| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50562696 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2080058 (CHEMBL4735849) |
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| Ki | 9.0±n/a nM |
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| Citation |  Staro?, J; Bugno, R; Pietru?, W; Sata?a, G; Mordalski, S; Warszycki, D; Hogendorf, A; Hogendorf, AS; Kalinowska-T?u?cik, J; Lenda, T; Pilarski, B; Bojarski, AJ Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT Eur J Med Chem209:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50562696 |
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| n/a |
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| Name | BDBM50562696 |
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| Synonyms: | CHEMBL4759208 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N3O2S |
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| Mol. Mass. | 355.454 |
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| SMILES | CN1CCN(CC1)c1ccc2ccn(c2c1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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