| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50565000 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2089913 (CHEMBL4771176) |
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| Ki | 688±n/a nM |
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| Citation |  Nizi, MG; Desantis, J; Nakatani, Y; Massari, S; Mazzarella, MA; Shetye, G; Sabatini, S; Barreca, ML; Manfroni, G; Felicetti, T; Rushton-Green, R; Hards, K; Latacz, G; Sata?a, G; Bojarski, AJ; Cecchetti, V; Kolá?, MH; Handzlik, J; Cook, GM; Franzblau, SG; Tabarrini, O Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. Eur J Med Chem201:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50565000 |
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| n/a |
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| Name | BDBM50565000 |
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| Synonyms: | CHEMBL4791959 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23Br2ClN2S |
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| Mol. Mass. | 518.736 |
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| SMILES | Cl.CN1CCCCC1CCN1c2ccc(Br)cc2Sc2cc(Br)ccc12 |
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| Structure | 
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