| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50137729 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_161070 (CHEMBL873425) |
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| Ki | 220±n/a nM |
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| Citation |  Victor, F; Lamar, J; Snyder, N; Yip, Y; Guo, D; Yumibe, N; Johnson, RB; Wang, QM; Glass, JI; Chen, SH P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl alpha-ketoamide based HCV protease inhibitors. Bioorg Med Chem Lett14:257-61 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44361.04 |
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| Organism: | Human rhinovirus B |
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| Description: | ChEMBL_158953 |
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| Residue: | 401 |
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| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
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| BDBM50137729 |
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| n/a |
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| Name | BDBM50137729 |
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| Synonyms: | (1S,5S,6R)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid (1-cyclopropylaminooxalyl-3,3-difluoro-propyl)-amide | CHEMBL84854 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H43F2N7O6 |
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| Mol. Mass. | 647.7132 |
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| SMILES | CC(C)[C@H](NC(=O)c1cnccn1)C(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H]2CCC[C@@H]2[C@H]1C(=O)NC(CC(F)F)C(=O)C(=O)NC1CC1 |
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| Structure | 
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