| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50177899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325740 (CHEMBL864530) |
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| Ki | 0.74±n/a nM |
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| Citation |  Henriksen, G; Platzer, S; Marton, J; Hauser, A; Berthele, A; Schwaiger, M; Marinelli, L; Lavecchia, A; Novellino, E; Wester, HJ Syntheses, biological evaluation, and molecular modeling of 18F-labeled 4-anilidopiperidines as mu-opioid receptor imaging agents. J Med Chem48:7720-32 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50177899 |
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| n/a |
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| Name | BDBM50177899 |
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| Synonyms: | CHEMBL371710 | methyl 4-[(N-1-oxopropyl)-N-phenylamino]-1-(5-[18F]-fluoropentyl)-4-piperidinecarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31FN2O3 |
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| Mol. Mass. | 378.4808 |
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| SMILES | CCC(=O)N(c1ccccc1)C1(CCN(CCCCCF)CC1)C(=O)OC |
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| Structure | 
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