| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50456168 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2239292 (CHEMBL5153188) |
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| IC50 | >10000±n/a nM |
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| Citation |  Wang, YH; Zhou, MZ; Ye, T; Wang, PP; Lu, R; Wang, YL; Liu, CX; Xiao, W; Li, JY; Meng, ZB; Xu, LL; Hu, QH; Jiang, C Discovery of a Series of 5-Amide-1 J Med Chem65:15967-15990 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50456168 |
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| n/a |
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| Name | BDBM50456168 |
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| Synonyms: | CHEMBL1800685 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H24F3NO2 |
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| Mol. Mass. | 475.5016 |
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| SMILES | OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F |
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| Structure | 
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