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TargetBcl-2-related protein A1
LigandBDBM50604877
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2249566 (CHEMBL5163776)
Ki 2900±n/a nM
Citation Feng, XYan, ZZhou, FLou, JLyu, XRen, XZeng, ZLiu, CZhang, SZhu, DHuang, HYang, JZhao, Y Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells. Eur J Med Chem236:0 (2022) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:Apoptosis regulator protein
Mol. Mass.:20130.01
Organism:Homo sapiens (Human)
Description:n/a
Residue:175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
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  Blast E-value cutoff:
BDBM50604877
n/a
NameBDBM50604877
Synonyms:CHEMBL5189912
TypeSmall organic molecule
Emp. Form.C22H21N3S
Mol. Mass.359.487
SMILESCSc1ccc(cc1)C(Nc1ccccn1)c1c(C)[nH]c2ccccc12
Structure
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