| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM50604881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2249570 (CHEMBL5163780) |
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| Ki | >100000±n/a nM |
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| Citation |  Feng, X; Yan, Z; Zhou, F; Lou, J; Lyu, X; Ren, X; Zeng, Z; Liu, C; Zhang, S; Zhu, D; Huang, H; Yang, J; Zhao, Y Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells. Eur J Med Chem236:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 20130.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 175 |
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| Sequence: | MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
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| BDBM50604881 |
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| n/a |
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| Name | BDBM50604881 |
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| Synonyms: | CHEMBL5175046 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27FN4O2 |
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| Mol. Mass. | 422.4952 |
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| SMILES | COCCCn1nc2cc(ccc2c1N1CCN(CC1)C(=O)C=C)-c1cccc(F)c1 |
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| Structure | 
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