| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 2 |
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| Ligand | BDBM50188779 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_389285 (CHEMBL868041) |
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| IC50 | 109000±n/a nM |
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| Citation |  Amarasinghe, KK; Evdokimov, AG; Evidokimov, AG; Xu, K; Clark, CM; Maier, MB; Srivastava, A; Colson, AO; Gerwe, GS; Stake, GE; Howard, BW; Pokross, ME; Gray, JL; Peters, KG Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. Bioorg Med Chem Lett16:4252-6 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 2 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 2 |
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| Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) |
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| Type: | Protein |
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| Mol. Mass.: | 48481.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P17706 |
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| Residue: | 415 |
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| Sequence: | MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
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| BDBM50188779 |
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| n/a |
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| Name | BDBM50188779 |
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| Synonyms: | CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(methoxycarbonyl)-4-oxobutyl]phenyl}sulfamate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20NO9S |
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| Mol. Mass. | 402.397 |
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| SMILES | CCOC(=O)CC(Cc1ccc(NS([O-])(=O)=O)cc1)(C(=O)OC)C(=O)OC |
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| Structure | 
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