| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine kinase 1 |
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| Ligand | BDBM50407507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2267125 |
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| Ki | 20000±n/a nM |
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| Citation |  Ding, T; Zhi, Y; Xie, W; Yao, Q; Liu, B Rational design of SphK inhibitors using crystal structures aided by computer. Eur J Med Chem213:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine kinase 1 |
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| Name: | Sphingosine kinase 1 |
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| Synonyms: | SK 1 | SPHK1_MOUSE | SPK 1 | Sk1 | Sphk1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42447.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_107622 |
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| Residue: | 382 |
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| Sequence: | MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASV
NHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLE
SEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPL
EEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLR
LFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWM
VCGSRDAPSGRDSRRGPPPEEP
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| BDBM50407507 |
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| n/a |
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| Name | BDBM50407507 |
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| Synonyms: | CHEMBL5281819 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N5O3 |
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| Mol. Mass. | 451.5612 |
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| SMILES | CCCCCCCCOc1ccc2cc(ccc2c1)-c1noc(n1)[C@@H]1[C@@H](O)CCN1C(N)=N |r| |
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| Structure | 
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