| Reaction Details |
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 | Report a problem with these data |
| Target | Steroidogenic factor 1 |
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| Ligand | BDBM50380592 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2267491 |
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| IC50 | 790±n/a nM |
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| Citation |  Liu, Z; Wang, P; Wold, EA; Song, Q; Zhao, C; Wang, C; Zhou, J Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer. J Med Chem64:4257-4288 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroidogenic factor 1 |
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| Name: | Steroidogenic factor 1 |
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| Synonyms: | AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP |
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| Type: | Nuclear Hormone Receptor |
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| Mol. Mass.: | 51643.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 461 |
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| Sequence: | MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
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| BDBM50380592 |
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| n/a |
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| Name | BDBM50380592 |
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| Synonyms: | CHEMBL1552719 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N6O2S |
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| Mol. Mass. | 456.52 |
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| SMILES | COc1ccc(cc1)-n1c(SCc2nc(no2)-c2ccc(C)cc2)nnc1-c1ccncc1 |
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| Structure | 
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