Reaction Details | |||
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Target | Leukotriene A-4 hydrolase | ||
Ligand | BDBM50251667 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_488465 (CHEMBL990998) | ||
IC50 | 220±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Leukotriene A-4 hydrolase | |||
Name: | Leukotriene A-4 hydrolase | ||
Synonyms: | LKHA4_HUMAN | LTA-4 hydrolase | LTA4 | LTA4H | Leukotriene A(4) hydrolase | Leukotriene A-4 hydrolase (LTA4H) | Leukotriene A4 hydrolase | ||
Type: | Hydrolase; metalloprotease | ||
Mol. Mass.: | 69280.41 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Human recombinant LTA4H. | ||
Residue: | 611 | ||
Sequence: |
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BDBM50251667 | |||
n/a | |||
Name | BDBM50251667 | ||
Synonyms: | 4-((4-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)cyclohexylamino)methyl)benzoic acid | CHEMBL479569 | ||
Type | Small organic molecule | ||
Emp. Form. | C29H29N3O4 | ||
Mol. Mass. | 483.5583 | ||
SMILES | OC(=O)c1ccc(CNC2CCC(CC2)Nc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1 |(15.61,-3.03,;15.6,-1.48,;16.91,-.7,;14.25,-.72,;12.93,-1.51,;11.59,-.75,;11.58,.78,;10.23,1.56,;8.89,.78,;7.55,1.55,;6.24,.76,;4.9,1.52,;4.89,3.07,;6.21,3.85,;7.55,3.1,;3.54,3.85,;2.2,3.07,;2.21,1.53,;.89,.75,;-.48,1.53,;-1.83,.77,;-3.16,1.57,;-4.5,.81,;-5.83,1.59,;-5.8,3.13,;-4.46,3.89,;-3.14,3.11,;-7.12,3.92,;-8.57,3.38,;-9.52,4.58,;-8.66,5.87,;-7.19,5.46,;-.47,3.07,;.86,3.85,;12.89,1.57,;14.23,.82,)| | ||
Structure | ![]() |