| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50288409 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210658 |
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| Ki | 2.5±n/a nM |
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| Citation |  Galemmo, RA; Fevig, JM; Carini, DJ; Cacciola, J; Wells, BL; Hillyer, GL; Jr., JB; Rossi, KA; Stouten, PF; Alexander, RS; Hilmer, R; Bostrom, L; Abelman, MM; Lee, SL; Weber, PC; Kettner, CA; Knabb, RM; Wexler, RR (N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors Bioorg Med Chem Lett6:2913-2918 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50288409 |
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| n/a |
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| Name | BDBM50288409 |
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| Synonyms: | CHEMBL99309 | N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-methyl]-N-phenethyl-3-phenyl-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H34BN3O4 |
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| Mol. Mass. | 439.355 |
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| SMILES | NCCCC[C@H](NC(=O)CN(CCc1ccccc1)C(=O)CCc1ccccc1)B(O)O |
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| Structure | 
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