| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50244093 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571690 (CHEMBL1032138) |
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| pH | 5±n/a |
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| Ki | 2200000±n/a nM |
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| Comments | extracted |
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| Citation |  Beck, J; Vercheval, L; Bebrone, C; Herteg-Fernea, A; Lassaux, P; Marchand-Brynaert, J Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate. Bioorg Med Chem Lett19:3593-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | BLAC_BACLI | blaP | penP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33993.80 |
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| Organism: | Bacillus licheniformis |
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| Description: | ChEMBL_571690 |
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| Residue: | 307 |
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| Sequence: | MKLWFSTLKLKKAAAVLLFSCVALAGCANNQTNASQPAEKNEKTEMKDDFAKLEEQFDAK
LGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYN
PITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFE
PELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVP
DGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMK
ALNMNGK
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| BDBM50244093 |
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| n/a |
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| Name | BDBM50244093 |
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| Synonyms: | 1-hydroxypropane-1,2,3-tricarboxylate | isocitrate | isocitrate(3-) |
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| Type | Small organic molecule |
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| Emp. Form. | C6H5O7 |
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| Mol. Mass. | 189.1013 |
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| SMILES | OC(C(CC([O-])=O)C([O-])=O)C([O-])=O |
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| Structure | 
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