| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
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| Ligand | BDBM50296437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_581553 (CHEMBL1060752) |
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| Ki | >25000±n/a nM |
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| Citation |  Hilfiker, MA; Wang, N; Hou, X; Du, Z; Pullen, MA; Nord, M; Nagilla, R; Fries, HE; Wu, CW; Sulpizio, AC; Jaworski, JP; Morrow, D; Edwards, RM; Jin, J Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists. Bioorg Med Chem Lett19:4292-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin F2-alpha receptor |
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| Name: | Prostaglandin F2-alpha receptor |
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| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40072.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43088 |
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| Residue: | 359 |
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| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
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| BDBM50296437 |
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| n/a |
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| Name | BDBM50296437 |
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| Synonyms: | CHEMBL557109 | N-(5-(pentan-3-yl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O3S |
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| Mol. Mass. | 333.405 |
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| SMILES | CCC(CC)c1nnc(NC(=O)c2ccc3OCCOc3c2)s1 |
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| Structure | 
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