| Reaction Details |
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 | Report a problem with these data |
| Target | Probable C-C chemokine receptor type 3 |
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| Ligand | BDBM50297171 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_581443 (CHEMBL1055687) |
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| IC50 | 230±n/a nM |
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| Citation |  Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Synthesis, biological evaluation, and metabolic stability of acrylamide derivatives as novel CCR3 antagonists. Bioorg Med Chem17:5989-6002 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable C-C chemokine receptor type 3 |
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| Name: | Probable C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 | CC-CKR-3 | CCR-3 | CCR3_MOUSE | CD_antigen=CD193 | CKR3 | Ccr3 | Cmkbr1l2 | Cmkbr3 | MIP-1 alpha RL2 | Macrophage inflammatory protein 1-alpha receptor-like 2 | Probable C-C chemokine receptor type 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41791.57 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1445729 |
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| Residue: | 359 |
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| Sequence: | MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVV
LILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLA
LYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQD
SFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHK
AIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCI
NPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
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| BDBM50297171 |
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| n/a |
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| Name | BDBM50297171 |
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| Synonyms: | CHEMBL551735 | N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxybenzoyl)piperidin-4-ylidene]acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H30FN3O3 |
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| Mol. Mass. | 487.5652 |
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| SMILES | [#8]-c1ccccc1-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]-c2ccc3cc(F)ccc3c2)-[#6]-1 |r| |
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| Structure | 
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