| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50300826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598758 (CHEMBL1040173) |
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| Ki | 88±n/a nM |
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| Citation |  Bernotas, RC; Lenicek, S; Antane, S; Cole, DC; Harrison, BL; Robichaud, AJ; Zhang, GM; Smith, D; Platt, B; Lin, Q; Li, P; Coupet, J; Rosenzweig-Lipson, S; Beyer, CE; Schechter, LE Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists. Bioorg Med Chem17:5153-63 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50300826 |
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| n/a |
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| Name | BDBM50300826 |
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| Synonyms: | 3-[(3-Fluorophenyl)sulfonyl]-1-(2-pyrrolidin-1-ylethyl)-1H-pyrrolo[2,3-b]pyridine | CHEMBL567805 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20FN3O2S |
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| Mol. Mass. | 373.444 |
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| SMILES | Fc1cccc(c1)S(=O)(=O)c1cn(CCN2CCCC2)c2ncccc12 |
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| Structure | 
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