| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50302145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598879 (CHEMBL1046455) |
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| EC50 | 114±n/a nM |
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| Citation |  Allerton, CM; Andrews, MD; Blagg, J; Ellis, D; Evrard, E; Green, MP; Liu, KK; McMurray, G; Ralph, M; Sanderson, V; Ward, R; Watson, L Design and synthesis of pyridazinone-based 5-HT(2C) agonists. Bioorg Med Chem Lett19:5791-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50302145 |
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| n/a |
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| Name | BDBM50302145 |
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| Synonyms: | (R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpiperazin-1-yl)pyridazin-3(2H)-one | CHEMBL570023 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21ClN4O2 |
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| Mol. Mass. | 348.827 |
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| SMILES | C[C@@H]1CNCCN1c1ccc(=O)n(CCOc2ccccc2Cl)n1 |r| |
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| Structure | 
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