Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50161646 ((1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells by scintillation counting | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342539 (2-(3-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301772 ((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA | Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342538 (2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azep...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50161646 ((1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342547 (2-(3-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342548 (2-(2-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 305 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342544 (2-(3-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 308 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50302145 ((R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpipera...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 325 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA | Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50302160 (6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 424 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA | Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342549 (2-(4-fluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50302151 ((S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 728 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA | Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50302141 (2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human recombinant 5HT2C receptor expressed in Swiss mouse 3T3 cells by SPA | Bioorg Med Chem Lett 19: 5791-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.136 BindingDB Entry DOI: 10.7270/Q2X0674Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50342545 (2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50089252 (CHEMBL3577889) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of dofetilide binding to human ERG | ACS Med Chem Lett 6: 419-24 (2015) Article DOI: 10.1021/ml500479v BindingDB Entry DOI: 10.7270/Q2FQ9ZBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50089251 (CHEMBL3576881) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >9.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of dofetilide binding to human ERG | ACS Med Chem Lett 6: 419-24 (2015) Article DOI: 10.1021/ml500479v BindingDB Entry DOI: 10.7270/Q2FQ9ZBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50089248 (CHEMBL3577881) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of dofetilide binding to human ERG | ACS Med Chem Lett 6: 419-24 (2015) Article DOI: 10.1021/ml500479v BindingDB Entry DOI: 10.7270/Q2FQ9ZBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50089253 (CHEMBL3577900) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of dofetilide binding to human ERG | ACS Med Chem Lett 6: 419-24 (2015) Article DOI: 10.1021/ml500479v BindingDB Entry DOI: 10.7270/Q2FQ9ZBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50089245 (CHEMBL3577885) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | >1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of dofetilide binding to human ERG | ACS Med Chem Lett 6: 419-24 (2015) Article DOI: 10.1021/ml500479v BindingDB Entry DOI: 10.7270/Q2FQ9ZBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM30547 (US8846698, 583) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.681 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM30449 (US8846698, 580) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.825 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM134792 (US8846698, 256) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135100 (US8846698, 526) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135053 (US8846698, 538) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.51 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135077 (US8846698, 564) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.57 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135051 (US8846698, 536) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.57 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135089 (US8846698, 577) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50294264 (CHEMBL562244 | rac-3-((biphenyl-2-yloxy)(piperidin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135043 (US8846698, 528) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135064 (US8846698, 551) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.78 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM186567 (US9163021, 235) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.87 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou... | US Patent US9163021 (2015) BindingDB Entry DOI: 10.7270/Q29C6W7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM186437 (US9163021, 95) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou... | US Patent US9163021 (2015) BindingDB Entry DOI: 10.7270/Q29C6W7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135083 (US8846698, 571) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135058 (US8846698, 545) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.95 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50294273 (CHEMBL562854 | rac-3-((2,3-dimethylphenoxy)(piperi...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50294287 (3-((2,3-dichlorophenoxy)((S)-piperidin-3-yl)methyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50294266 (CHEMBL550696 | rac-3-((3-chlorophenoxy)(piperidin-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50294272 (CHEMBL563987 | rac-3-((2,3-difluorophenoxy)(piperi...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50294287 (3-((2,3-dichlorophenoxy)((S)-piperidin-3-yl)methyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM134750 (US8846698, 213 | US8846698, 215) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.03 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135087 (US8846698, 575) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM186376 (US9163021, 33) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou... | US Patent US9163021 (2015) BindingDB Entry DOI: 10.7270/Q29C6W7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135076 (US8846698, 563) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135069 (US8846698, 556) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM30532 (US8846698, 581) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM135062 (US8846698, 549) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM134787 (US8846698, 250) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM134603 (US8846698, 66) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.55 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM134763 (US8846698, 226) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.61 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... | US Patent US8846698 (2014) BindingDB Entry DOI: 10.7270/Q2F47MTW | |||||||||||
More data for this Ligand-Target Pair |
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