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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cholinesterase | ||
| Ligand | BDBM50307927 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_608063 (CHEMBL1072133) | ||
| IC50 | 10000±n/a nM | ||
| Citation |  Alptüzün, V; Prinz, M; Hörr, V; Scheiber, J; Radacki, K; Fallarero, A; Vuorela, P; Engels, B; Braunschweig, H; Erciyas, E; Holzgrabe, U Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases. Bioorg Med Chem18:2049-59 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cholinesterase | |||
| Name: | Cholinesterase | ||
| Synonyms: | BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 65643.35 | ||
| Organism: | Equus caballus (Horse) | ||
| Description: | P81908 | ||
| Residue: | 574 | ||
| Sequence: |
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| BDBM50307927 | |||
| n/a | |||
| Name | BDBM50307927 | ||
| Synonyms: | 4-((2,6-dichlorobenzylidene)hydrazono)-1-(3-phenylpropyl)-1,4-dihydropyridine | CHEMBL597993 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H19Cl2N3 | ||
| Mol. Mass. | 384.302 | ||
| SMILES | Clc1cccc(Cl)c1\C=N\N=c1ccn(CCCc2ccccc2)cc1 |(14.77,-30.22,;13.43,-30.99,;12.1,-30.22,;10.77,-31,;10.77,-32.54,;12.11,-33.3,;12.12,-34.84,;13.43,-32.53,;14.77,-33.3,;16.1,-32.53,;17.43,-33.29,;18.77,-32.52,;20.1,-33.29,;21.43,-32.52,;21.43,-30.98,;22.77,-30.22,;24.1,-30.99,;25.44,-30.22,;26.77,-31,;26.75,-32.54,;28.09,-33.31,;29.42,-32.54,;29.42,-30.99,;28.09,-30.23,;20.1,-30.21,;18.76,-30.98,)| | ||
| Structure | 
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