| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase SHV-5 |
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| Ligand | BDBM50347180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_754353 (CHEMBL1799219) |
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| IC50 | >50000±n/a nM |
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| Citation |  Tan, Q; Ogawa, AM; Raghoobar, SL; Wisniewski, D; Colwell, L; Park, YW; Young, K; Hermes, JD; Dininno, FP; Hammond, ML Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii. Bioorg Med Chem Lett21:4363-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase SHV-5 |
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| Name: | Beta-lactamase SHV-5 |
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| Synonyms: | BLA5_KLEPN | bla | shv5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31257.78 |
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| Organism: | Klebsiella pneumoniae |
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| Description: | ChEMBL_754353 |
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| Residue: | 286 |
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| Sequence: | MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE
RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA
AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA
SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARG
IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
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| BDBM50347180 |
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| n/a |
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| Name | BDBM50347180 |
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| Synonyms: | CHEMBL1795563 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13FN5O5PS |
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| Mol. Mass. | 413.321 |
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| SMILES | CO\N=C(/C(=O)NCP(O)(=O)Oc1ccc(C#N)c(F)c1)c1cnc(N)s1 |
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| Structure | 
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