| Reaction Details |
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 | Report a problem with these data |
| Target | Oxa40 |
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| Ligand | BDBM50347188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_754356 (CHEMBL1799222) |
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| IC50 | 27000±n/a nM |
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| Citation |  Tan, Q; Ogawa, AM; Raghoobar, SL; Wisniewski, D; Colwell, L; Park, YW; Young, K; Hermes, JD; Dininno, FP; Hammond, ML Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii. Bioorg Med Chem Lett21:4363-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxa40 |
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| Name: | Oxa40 |
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| Synonyms: | Beta-lactamase | Class D β-lactamase (OXA-24) |
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| Type: | Enzyme |
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| Mol. Mass.: | 30946.50 |
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| Organism: | Acinetobacter baumannii |
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| Description: | Q8RLA6 |
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| Residue: | 275 |
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| Sequence: | MKKFILPIFSISILVSLSACSSIKTKSEDNFHISSQQHEKAIKSYFDEAQTQGVIIIKEG
KNLSTYGNALARANKEYVPASTFKMLNALIGLENHKATTNEIFKWDGKKRTYPMWEKDMT
LGEAMALSAVPVYQELARRTGLELMQKEVKRVNFGNTNIGTQVDNFWLVGPLKITPVQEV
NFADDLAHNRLPFKLETQEEVKKMLLIKEVNGSKIYAKSGWGMGVTPQVGWLTGWVEQAN
GKKIPFSLNLEMKEGMSGSIRNEITYKSLENLGII
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| BDBM50347188 |
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| n/a |
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| Name | BDBM50347188 |
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| Synonyms: | CHEMBL1795571 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20FN4O5PS |
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| Mol. Mass. | 502.455 |
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| SMILES | [O-]P(=O)(CNC(=O)C(=N/OCCC[n+]1ccccc1)\c1cccs1)Oc1ccc(C#N)c(F)c1 |
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| Structure | 
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