| Reaction Details |
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 | Report a problem with these data |
| Target | Melanin-concentrating hormone receptor 2 |
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| Ligand | BDBM50360689 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795932 (CHEMBL1936805) |
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| IC50 | 100±n/a nM |
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| Citation |  Chen, X; Mihalic, J; Fan, P; Liang, L; Lindstrom, M; Wong, S; Ye, Q; Fu, Y; Jaen, J; Chen, JL; Dai, K; Li, L Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2. Bioorg Med Chem Lett22:363-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanin-concentrating hormone receptor 2 |
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| Name: | Melanin-concentrating hormone receptor 2 |
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| Synonyms: | GPR145 | MCHR2 | MCHR2_HUMAN | Melanin Concentrating Hormone 2 | Melanin-concentrating hormone receptor | Melanin-concentrating hormone receptor 2 | SLT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38862.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Melanin Concentrating Hormone 2 GPR145 HUMAN::Q969V1 |
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| Residue: | 340 |
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| Sequence: | MNPFHASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTII
RSRKKTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFAC
SAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLWAASFILALPVWVYSKVIKFKDG
VESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPS
VPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSS
INPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF
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| BDBM50360689 |
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| n/a |
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| Name | BDBM50360689 |
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| Synonyms: | CHEMBL1934107 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N2 |
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| Mol. Mass. | 364.4822 |
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| SMILES | C(N1CCC2(CC1)C=Cc1ccccc21)c1ccc2[nH]c3ccccc3c2c1 |c:8| |
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| Structure | 
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