| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50406795 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_217980 (CHEMBL824099) |
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| Ki | 9±n/a nM |
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| Citation |  Atwal, KS; Ahmed, SZ; Bird, JE; Delaney, CL; Dickinson, KE; Ferrara, FN; Hedberg, A; Miller, AV; Moreland, S; O'Reilly, BC Dihydropyrimidine angiotensin II receptor antagonists. J Med Chem35:4751-63 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50406795 |
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| n/a |
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| Name | BDBM50406795 |
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| Synonyms: | Cozaar | LOSARTAN POTASSIUM |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClN6O |
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| Mol. Mass. | 421.903 |
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| SMILES | CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1 |
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| Structure | 
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