| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 1 |
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| Ligand | BDBM50129647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105134 (CHEMBL715018) |
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| IC50 | >100000±n/a nM |
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| Citation |  Luo, QL; Li, JY; Liu, ZY; Chen, LL; Li, J; Qian, Z; Shen, Q; Li, Y; Lushington, GH; Ye, QZ; Nan, FJ Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. J Med Chem46:2631-40 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 1 |
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| Name: | Methionine aminopeptidase 1 |
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| Synonyms: | MAP 1 | MAP1 | MAP1_YEAST | MetAP 1 | Peptidase M 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43382.92 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_10701 |
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| Residue: | 387 |
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| Sequence: | MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYK
AHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQR
NDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYP
SPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGEN
ISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFF
HCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHT
LLVTEHGVEILTARNKKSPGGPRQRIK
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| BDBM50129647 |
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| n/a |
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| Name | BDBM50129647 |
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| Synonyms: | 3-(4-Fluoro-benzoylamino)-pyridine-2-carboxylic acid thiazol-2-ylamide | CHEMBL329320 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11FN4O2S |
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| Mol. Mass. | 342.348 |
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| SMILES | Fc1ccc(cc1)C(=O)Nc1cccnc1C(=O)Nc1nccs1 |
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| Structure | 
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