| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
|---|
| Ligand | BDBM50375019 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_470173 (CHEMBL921354) |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Synthesis and structure-activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists. Bioorg Med Chem16:144-56 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-C chemokine receptor type 3 |
|---|
| Name: | C-C chemokine receptor type 3 |
|---|
| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41053.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P51677 |
|---|
| Residue: | 355 |
|---|
| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
|
|
|
|---|
| BDBM50375019 |
|---|
| n/a |
|---|
| Name | BDBM50375019 |
|---|
| Synonyms: | CHEMBL258996 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H29FN2O |
|---|
| Mol. Mass. | 464.5732 |
|---|
| SMILES | Fc1ccc2cc(CN3[C@H]4CC[C@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 |THB:16:14:8:10.11| |
|---|
| Structure | 
|
|---|
Search and Browse
