| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50387907 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830706 (CHEMBL2061693) |
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| EC50 | 139±n/a nM |
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| Citation |  Sakairi, M; Kogami, M; Torii, M; Kataoka, H; Fujieda, H; Makino, M; Kataoka, D; Okamoto, R; Miyazawa, T; Okabe, M; Inoue, M; Takahashi, N; Harada, S; Watanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett22:5123-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | GP119_MOUSE | Gpr119 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37009.07 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1506420 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
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| BDBM50387907 |
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| n/a |
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| Name | BDBM50387907 |
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| Synonyms: | CHEMBL2058668 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O4 |
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| Mol. Mass. | 410.4662 |
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| SMILES | COC(=O)c1cnc(nc1)N1CCC(CCCNc2ccc3c(O)coc3c2)CC1 |
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| Structure | 
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