| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 142 |
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| Ligand | BDBM50395776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_860252 (CHEMBL2169193) |
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| EC50 | 1.8±n/a nM |
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| Citation |  Du, X; Kim, YJ; Lai, S; Chen, X; Lizarzaburu, M; Turcotte, S; Fu, Z; Liu, Q; Zhang, Y; Motani, A; Oda, K; Okuyama, R; Nara, F; Murakoshi, M; Fu, A; Reagan, JD; Fan, P; Xiong, Y; Shen, W; Li, L; Houze, J; Medina, JC Phenylalanine derivatives as GPR142 agonists for the treatment of type II diabetes. Bioorg Med Chem Lett22:6218-23 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 142 |
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| Name: | Probable G-protein coupled receptor 142 |
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| Synonyms: | GP142_MOUSE | Gpr142 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40779.27 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_985965 |
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| Residue: | 365 |
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| Sequence: | MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPES
PERSPCVAGIIPVIYYSVLLSLGLPVALARLAARTRKPSYHYLLALTASDIVTQVIIVFV
GFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPG
RTHRAIAAVIGVTLLTGIPFYWWLDVWRDADPPSTMDKLLKWAHCLIVYFIPCNVFLVTN
SAIILRLRKRGQRGLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWRVH
LALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQTVVELMLKS
VGTEL
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| BDBM50395776 |
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| n/a |
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| Name | BDBM50395776 |
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| Synonyms: | CHEMBL2164850 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N5O2 |
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| Mol. Mass. | 451.5197 |
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| SMILES | O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NC1(CC1)c1ccccn1 |r| |
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| Structure | 
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